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WormBase Tree Display for Gene: WBGene00015176

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Name Class

WBGene00015176SMapS_parentSequenceB0414
IdentityVersion2
NameCGC_namevps-51Person_evidenceWBPerson3132
Sequence_nameB0414.8
Molecular_nameB0414.8a
B0414.8a.1
CE30413
B0414.8b
CE36910
B0414.8b.1
Other_nameCELE_B0414.8Accession_evidenceNDBBX284601
Public_namevps-51
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
204 Jan 2010 16:36:03WBPerson2970Name_changeCGC_namevps-51
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classvps
Allele (35)
StrainWBStrain00034980
RNASeq_FPKM (74)
GO_annotation (33)
Contained_in_operonCEOP1003
Ortholog (39)
Structured_descriptionConcise_descriptionvps-51 encodes the C. elegans ortholog of the yeast Vps51p GARP (Golgi associated retrograde protein) complex subunit; in C. elegans, VPS-51 forms a GARP complex with VPS-52, VPS-53, and VPS-54; vps-51 is ubiquitously expressed, with particularly strong expression seen in neurons.Paper_evidenceWBPaper00038455
Curator_confirmedWBPerson1843
Date_last_updated13 Jan 2012 00:00:00
Automated_descriptionEnables syntaxin binding activity. Involved in negative regulation of dense core granule transport; positive regulation of dense core granule transport; and positive regulation of locomotion involved in locomotory behavior. Part of GARP complex. Expressed in body wall musculature; intestinal cell; and neurons. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 13. Is an ortholog of human VPS51 (VPS51 subunit of GARP complex).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112332Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1172)
Molecular_infoCorresponding_CDSB0414.8a
B0414.8b
Corresponding_CDS_historyB0414.8:wp126
Corresponding_transcriptB0414.8a.1
B0414.8b.1
Other_sequence (48)
Associated_featureWBsf649190
WBsf664278
WBsf219485
Experimental_infoRNAi_resultWBRNAi00002858Inferred_automaticallyRNAi_primary
WBRNAi00039043Inferred_automaticallyRNAi_primary
WBRNAi00085078Inferred_automaticallyRNAi_primary
WBRNAi00028135Inferred_automaticallyRNAi_primary
WBRNAi00117031Inferred_automaticallyRNAi_primary
WBRNAi00076054Inferred_automaticallyRNAi_primary
WBRNAi00062092Inferred_automaticallyRNAi_primary
Expr_patternExpr9332
Expr9335
Expr1026287
Expr1036498
Expr1143203
Expr1200264
Expr2018034
Expr2036171
Drives_constructWBCnstr00013908
WBCnstr00029029
Construct_productWBCnstr00029029
Microarray_results (23)
Expression_cluster (83)
Interaction (72)
Map_infoMapIPosition0.457332Error0.001591
PositivePositive_cloneB0414Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038455
WBPaper00038491
WBPaper00055090
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene