WormBase Tree Display for Gene: WBGene00015135
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| WBGene00015135 | SMap | S_parent | Sequence | B0304 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyp-23A1 | |||||||
| Sequence_name | B0304.3 | ||||||||
| Molecular_name | B0304.3 | ||||||||
| B0304.3.1 | |||||||||
| CE27050 | |||||||||
| Other_name | CELE_B0304.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | cyp-23A1 | ||||||||
| DB_info | Database | AceView | gene | 2E805 | |||||
| WormQTL | gene | WBGene00015135 | |||||||
| WormFlux | gene | WBGene00015135 | |||||||
| NDB | locus_tag | CELE_B0304.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00015135|UniProtKB=Q27465 | |||||||
| family | PTHR24300 | ||||||||
| NCBI | gene | 173787 | |||||||
| RefSeq | protein | NM_062396.7 | |||||||
| TrEMBL | UniProtAcc | Q27465 | |||||||
| UniProt_GCRP | UniProtAcc | Q27465 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-23A1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele | WBVar00726334 | ||||||||
| WBVar00726335 | |||||||||
| WBVar00726336 | |||||||||
| WBVar01499702 | |||||||||
| WBVar00726337 | |||||||||
| WBVar00726338 | |||||||||
| WBVar00726339 | |||||||||
| WBVar00726340 | |||||||||
| WBVar00171532 | |||||||||
| WBVar00171533 | |||||||||
| WBVar00171535 | |||||||||
| WBVar00171536 | |||||||||
| WBVar01498435 | |||||||||
| WBVar01371712 | |||||||||
| WBVar01916660 | |||||||||
| WBVar00145660 | |||||||||
| WBVar01916662 | |||||||||
| WBVar01393550 | |||||||||
| WBVar00260974 | |||||||||
| WBVar01393551 | |||||||||
| WBVar00260977 | |||||||||
| WBVar01239252 | |||||||||
| WBVar01239254 | |||||||||
| WBVar00550206 | |||||||||
| WBVar00261729 | |||||||||
| WBVar00261730 | |||||||||
| WBVar00275640 | |||||||||
| WBVar01437520 | |||||||||
| WBVar01437521 | |||||||||
| WBVar01437522 | |||||||||
| WBVar01783075 | |||||||||
| WBVar01489705 | |||||||||
| WBVar00103610 | |||||||||
| WBVar00103611 | |||||||||
| WBVar00103612 | |||||||||
| WBVar00364226 | |||||||||
| WBVar00364227 | |||||||||
| WBVar00364228 | |||||||||
| WBVar00364229 | |||||||||
| WBVar00364230 | |||||||||
| WBVar00364231 | |||||||||
| WBVar00364232 | |||||||||
| WBVar02078223 | |||||||||
| WBVar00364233 | |||||||||
| WBVar00364234 | |||||||||
| WBVar00726324 | |||||||||
| WBVar00726325 | |||||||||
| WBVar00726326 | |||||||||
| WBVar00726327 | |||||||||
| WBVar00726328 | |||||||||
| WBVar00726329 | |||||||||
| WBVar00726330 | |||||||||
| WBVar00726331 | |||||||||
| WBVar00726332 | |||||||||
| WBVar00726333 | |||||||||
| Strain | WBStrain00035808 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (57) | |||||||||
| Paralog (44) | |||||||||
| Structured_description | Concise_description | cyp-23A1 encodes a cytochrome P450 homologous to the human gene CYP7B1, which when mutated leads to giant cell hepatitis (OMIM:231100); as a cytochrome P450, CYP-23A1 is predicted to function as a membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyzes the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:783 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2622) | ||||
| DOID:1073 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2622) | ||||||
| Molecular_info | Corresponding_CDS | B0304.3 | |||||||
| Corresponding_transcript | B0304.3.1 | ||||||||
| Other_sequence (11) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00103146 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00038912 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092638 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078391 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00009688 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1028987 | ||||||||
| Expr1036472 | |||||||||
| Expr1143092 | |||||||||
| Expr2010695 | |||||||||
| Expr2028934 | |||||||||
| Drives_construct | WBCnstr00029059 | ||||||||
| Construct_product | WBCnstr00029059 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (131) | |||||||||
| Interaction | WBInteraction000050741 | ||||||||
| WBInteraction000557101 | |||||||||
| Map_info | Map | II | Position | -4.29115 | Error | 0.046 | |||
| Positive | Positive_clone | B0304 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5366 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027704 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049383 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
