WormBase Tree Display for Gene: WBGene00014965

WBGene00014965 SMap: S_parent: Sequence: Y106G6D
  Identity: Version: 2
    Name: Sequence_name: Y106G6D.5
      Molecular_name: Y106G6D.5a
        Y106G6D.5a.1
        CE50264
        Y106G6D.5b
        CE50220
        Y106G6D.5b.1
        Y106G6D.5c
        Y106G6D.5d
      Other_name: CELE_Y106G6D.5 Accession_evidence: NDB BX284601
      Public_name: Y106G6D.5
    DB_info: Database: WormQTL gene WBGene00014965
        NDB locus_tag CELE_Y106G6D.5
        Panther gene CAEEL|WormBase=Y106G6D.5a|UniProtKB=A0A0K2WNK1
          family PTHR10887
        NCBI gene 13181740
        RefSeq protein NR_132563.1
            NM_001383712.1
            NM_001313461.3
            NR_132564.1
        TrEMBL UniProtAcc A0A0K2WNK1
            A0A0K2WN06
        UniProt_GCRP UniProtAcc A0A0K2WNK1
        OMIM gene 600502
        RNAcentral URSid URS000083AAAE
            URS00008454B6
    Species: Caenorhabditis elegans
    History: Version_change: 1 27 May 2004 15:23:24 WBPerson1971 Event: Imported: Initial conversion from Pseudogene class of WS125
        2 18 Sep 2014 13:15:09 WBPerson1983 Event: Changed_class: Pseudogene CDS
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (46)
    RNASeq_FPKM (74)
    GO_annotation: 00000560
      00000561
      00000562
      00000563
      00000564
      00000565
      00000566
      00000567
      00120999
    Ortholog (36)
    Paralog: WBGene00001016 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001258 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004880 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007329 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008099 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00010989 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00014208 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016565 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016566 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable RNA binding activity and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in termination of RNA polymerase II transcription. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2S and distal spinal muscular atrophy 1. Is an ortholog of human IGHMBP2 (immunoglobulin mu DNA binding protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111064 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5542)
      DOID:0110171 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5542)
  Molecular_info: Corresponding_CDS: Y106G6D.5a
      Y106G6D.5b
    Corresponding_CDS_history: Y106G6D.5:wp101
    Corresponding_transcript: Y106G6D.5c
      Y106G6D.5d
      Y106G6D.5a.1
      Y106G6D.5b.1
    Corresponding_pseudogene_history: Y106G6D.5a:wp245
      Y106G6D.5b:wp245
    Other_sequence (29)
    Associated_feature: WBsf649549
      WBsf649550
      WBsf664838
      WBsf984918
      WBsf1010490
  Experimental_info: RNAi_result: WBRNAi00117028 Inferred_automatically: RNAi_primary
      WBRNAi00055254 Inferred_automatically: RNAi_primary
      WBRNAi00002235 Inferred_automatically: RNAi_primary
      WBRNAi00004497 Inferred_automatically: RNAi_primary
      WBRNAi00004496 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2006987
      Expr2025209
    Microarray_results (14)
    Expression_cluster: WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00061340:URA_parent
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:Y45F10D.7-C14C10.4
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064716:paraquat_upregulated
      WBPaper00065258:anchor-cell_depleted
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_9
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032948:StarveUp2
      WBPaper00034661:AgNPs_upregulated
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00037695:WC_5-day
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040821:Au-NP_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042204:Comamonas_DA1877_upregulated
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042258:DA1877_upregulated_YoungAdult
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Fed
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecium_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:herm_sex-enriched
  Map_info: Positive: Positive_clone: Y106G6D Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 4.65979
  Reference: WBPaper00055090
    WBPaper00064339
  Method: Gene