WormBase Tree Display for Gene: WBGene00013972

WBGene00013972 SMap: S_parent: Sequence: ZK384
  Identity: Version: 3
    Name: CGC_name: scl-20 Person_evidence: WBPerson261
      Sequence_name: ZK384.2
      Molecular_name: ZK384.2
        ZK384.2.1
        CE16723
      Other_name: dct-2 Paper_evidence: WBPaper00031095
        CELE_ZK384.2 Accession_evidence: NDB BX284605
      Public_name: scl-20
    DB_info: Database: AceView gene 5T208
        WormQTL gene WBGene00013972
        WormFlux gene WBGene00013972
        NDB locus_tag CELE_ZK384.2
        Panther gene CAEEL|WormBase=WBGene00013972|UniProtKB=O62508
          family PTHR10334
        NCBI gene 191309
        RefSeq protein NM_075254.2
        TREEFAM TREEFAM_ID TF352352
        TrEMBL UniProtAcc O62508
        UniProt_GCRP UniProtAcc O62508
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 07 Nov 2007 11:51:23 WBPerson2970 Name_change: CGC_name: scl-20
        3 08 Nov 2007 16:33:50 WBPerson2970 Name_change: Other_name: dct-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: scl
    Allele (55)
    RNASeq_FPKM (74)
    GO_annotation: 00038014
    Ortholog (46)
    Paralog (32)
    Structured_description: Concise_description: scl-20 encodes a predicted extracellular protein that is a member of the C. elegans family of SCP/TAPS domain-containing proteins; SCL-20 is homologous to mammalian GliPR1, a p53 target with proapoptotic activity mediated by an increase in production of reactive oxygen species; loss of scl-20 activity via RNAi in daf-2 mutants and in gld-1;daf-2 doubly mutant animals indicates that, in C. elegans, scl-20 can function to regulate both lifespan and tumor cell proliferation; scl-20 contains five DAF-16 consensus binding sites within 5kb of its promoter. Paper_evidence: WBPaper00031095
            WBPaper00031679
          Curator_confirmed: WBPerson1843
          Date_last_updated: 16 Apr 2008 00:00:00
      Automated_description: Predicted to be located in extracellular space. Is an ortholog of human GLIPR1 (GLI pathogenesis related 1) and R3HDML (R3H domain containing like). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK384.2
    Corresponding_transcript: ZK384.2.1
    Other_sequence: JI211495.1
  Experimental_info: RNAi_result: WBRNAi00021994 Inferred_automatically: RNAi_primary
      WBRNAi00059398 Inferred_automatically: RNAi_primary
      WBRNAi00038281 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021827
      Expr1162824
      Expr2015632
      Expr2033867
    Drives_construct: WBCnstr00029402
    Construct_product: WBCnstr00029402
    Microarray_results (16)
    Expression_cluster (108)
    Interaction: WBInteraction000122982
      WBInteraction000123334
      WBInteraction000467581
      WBInteraction000467582
      WBInteraction000472342
  Map_info: Map: V Position: 17.5135 Error: 0.027335
    Positive: Positive_clone: ZK384 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031095
    WBPaper00038491
    WBPaper00040160
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene