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WormBase Tree Display for Gene: WBGene00013920

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Name Class

WBGene00013920SMapS_parentSequenceZC506
IdentityVersion2
NameCGC_namepssy-1Person_evidenceWBPerson1105
Sequence_nameZC506.3
Molecular_nameZC506.3
ZC506.3.1
CE01681
ZC506.3.2
Other_nameCELE_ZC506.3Accession_evidenceNDBBX284606
Public_namepssy-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
202 Mar 2006 11:42:04WBPerson2970Name_changeCGC_namepssy-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpssy
Allele (53)
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOPX107
Ortholog (35)
ParalogWBGene00012095Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00012897Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionpssy-1 encodes a phosphatidylserine (PS) synthase; by homology, PSSY-1 is predicted to function in the biosynthesis of phosphatidylserine; loss of pssy-1 function suppresses endocytic recyling defects in animals containing a mutation in tat-1, a P4-ATPase that functions to transport phosphatidylserine and in animals overexpressing NUM-1A, an isoform of the C. elegans Numb ortholog.Paper_evidenceWBPaper00040189
Curator_confirmedWBPerson1843
Date_last_updated14 Oct 2011 00:00:00
Automated_descriptionPredicted to enable L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Is an ortholog of human PTDSS1 (phosphatidylserine synthase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111507Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9587)
Molecular_infoCorresponding_CDSZC506.3
Corresponding_transcriptZC506.3.1
ZC506.3.2
Other_sequence (26)
Associated_featureWBsf648437
WBsf663213
WBsf1006580
WBsf236223
WBsf236224
WBsf236225
WBsf236226
Experimental_infoRNAi_resultWBRNAi00058984Inferred_automaticallyRNAi_primary
WBRNAi00087512Inferred_automaticallyRNAi_primary
WBRNAi00001747Inferred_automaticallyRNAi_primary
WBRNAi00038086Inferred_automaticallyRNAi_primary
Expr_patternChronogram2083
Expr7173
Expr1024311
Expr1036228
Expr1162417
Expr2015137
Expr2033375
Drives_constructWBCnstr00003699
WBCnstr00029444
Construct_productWBCnstr00029444
Microarray_results (22)
Expression_cluster (107)
InteractionWBInteraction000286504
WBInteraction000287546
WBInteraction000308997
WBInteraction000317134
WBInteraction000378737
WBInteraction000389768
Map_infoMapXPosition1.73168
PositivePositive_cloneZC506Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00040189
WBPaper00042257
WBPaper00055090
WBPaper00060347
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene