WormBase Tree Display for Gene: WBGene00013737
expand all nodes | collapse all nodes | view schema
| WBGene00013737 | SMap | S_parent | Sequence | Y111B2A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | tpst-1 | Person_evidence | WBPerson1855 | |||||
| Sequence_name | Y111B2A.15 | ||||||||
| Molecular_name | Y111B2A.15 | ||||||||
| Y111B2A.15.1 | |||||||||
| CE26632 | |||||||||
| Other_name | TPST-A | Paper_evidence | WBPaper00024673 | ||||||
| CELE_Y111B2A.15 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | tpst-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 20 Dec 2007 11:31:35 | WBPerson2970 | Name_change | CGC_name | tpst-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tpst | ||||||||
| Allele (244) | |||||||||
| Strain | WBStrain00051381 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Contained_in_operon | CEOP3799 | ||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00018365 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | tpst-1 encodes a tyrosylprotein sulfotransferase; tpst-1 activity is required for proper cuticle formation and secretion of ROL-6, a cuticle collagen; when expressed in 293-T cells, TPST-1 exhibits tyrosylprotein sulfotransferase activity; a tpst-1::gfp promoter fusion is expressed beginning during embryogenesis and continuing through larval and adult stages; tpst-1 expression is seen mainly in the hypodermis, particularly the seam cells, and in head neurons. | Paper_evidence | WBPaper00003269 | |||||
| WBPaper00024673 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 18 Mar 2010 00:00:00 | ||||||||
| Automated_description | Enables protein-tyrosine sulfotransferase activity. Involved in several processes, including collagen metabolic process; cuticle development involved in collagen and cuticulin-based cuticle molting cycle; and regulation of nematode larval development. Located in trans-Golgi network. Expressed in AIYL; AIYR; head neurons; and hypodermis. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human TPST1 (tyrosylprotein sulfotransferase 1) and TPST2 (tyrosylprotein sulfotransferase 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050861 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12020) | ||||
| Molecular_info | Corresponding_CDS | Y111B2A.15 | |||||||
| Corresponding_transcript | Y111B2A.15.1 | ||||||||
| Other_sequence (20) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr3129 | ||||||||
| Expr9008 | |||||||||
| Expr10091 | |||||||||
| Expr1028929 | |||||||||
| Expr1036155 | |||||||||
| Expr1158877 | |||||||||
| Expr2017472 | |||||||||
| Expr2035611 | |||||||||
| Drives_construct | WBCnstr00007687 | ||||||||
| WBCnstr00011157 | |||||||||
| WBCnstr00015063 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (100) | |||||||||
| Interaction | WBInteraction000008349 | ||||||||
| WBInteraction000008350 | |||||||||
| WBInteraction000008351 | |||||||||
| WBInteraction000008352 | |||||||||
| WBInteraction000051759 | |||||||||
| WBInteraction000504330 | |||||||||
| WBInteraction000552957 | |||||||||
| Map_info | Map | III | Position | 18.0854 | Error | 0.017021 | |||
| Positive | Positive_clone | Y111B2A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003269 | ||||||||
| WBPaper00024673 | |||||||||
| WBPaper00035539 | |||||||||
| WBPaper00036033 | |||||||||
| WBPaper00036035 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
