WormBase Tree Display for Gene: WBGene00013311

WBGene00013311 SMap: S_parent: Sequence: Y57G11C
  Identity: Version: 3
    Name: CGC_name: sec-61.A Person_evidence: WBPerson1983
      Sequence_name: Y57G11C.15
      Molecular_name: Y57G11C.15a
        Y57G11C.15a.1
        CE14954
        Y57G11C.15b
        CE46476
        Y57G11C.15b.1
      Other_name: sec-61
        CELE_Y57G11C.15 Accession_evidence: NDB BX284604
      Public_name: sec-61.A
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Aug 2013 16:41:57 WBPerson2970 Name_change: CGC_name: sec-61
        3 20 May 2019 14:10:26 WBPerson1983 Name_change: CGC_name: sec-61.A
                Other_name: sec-61
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sec
    Allele (56)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog: WBGene00040256 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00070811 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00040253 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00149156 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00122235 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00106870 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
      WBGene00073627 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00073628 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00075635 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00073631 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00070807 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00070806 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00070805 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00070804 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00234102 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g8771 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g11710 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g9464 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7551 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g3434 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g15823 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g637 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13705 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g15395 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g5485 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_23165.g26964 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_IV.g12400 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g15275 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_02078.g24745 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_15907 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_012858 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02797 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40181700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12544 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00241570 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00090583 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00105843 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00114555 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00275351 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00276774 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00277094 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00278131 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00278132 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00281506 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00281509 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00281697 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00285006 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297992 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000004370 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0086357 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-020418-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-021016-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:18276 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:17702 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1858417 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1931071 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:68321 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1305948 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of Sec61 translocon complex. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Is an ortholog of human SEC61A1 (SEC61 translocon subunit alpha 1) and SEC61A2 (SEC61 translocon subunit alpha 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060062 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18276)
  Molecular_info: Corresponding_CDS: Y57G11C.15a
      Y57G11C.15b
    Corresponding_transcript: Y57G11C.15a.1
      Y57G11C.15b.1
    Other_sequence (346)
    Associated_feature (13)
  Experimental_info: RNAi_result: WBRNAi00117219 Inferred_automatically: RNAi_primary
      WBRNAi00000312 Inferred_automatically: RNAi_primary
      WBRNAi00022997 Inferred_automatically: RNAi_primary
      WBRNAi00000220 Inferred_automatically: RNAi_primary
      WBRNAi00085592 Inferred_automatically: RNAi_primary
      WBRNAi00057687 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013952
      Expr1035938
      Expr1161099
      Expr2015719
      Expr2033951
    Drives_construct: WBCnstr00029694
    Construct_product: WBCnstr00029694
    Microarray_results (26)
    Expression_cluster (213)
    Interaction (171)
  Map_info: Map: IV Position: 12.5297
    Positive: Positive_clone: Y57G11C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031214
    WBPaper00032322
    WBPaper00033545
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene