WormBase Tree Display for Gene: WBGene00013311

WBGene00013311 SMap: S_parent: Sequence: Y57G11C
  Identity: Version: 3
    Name: CGC_name: sec-61.A Person_evidence: WBPerson1983
      Sequence_name: Y57G11C.15
      Molecular_name: Y57G11C.15a
        Y57G11C.15a.1
        CE14954
        Y57G11C.15b
        CE46476
        Y57G11C.15b.1
      Other_name: sec-61
        CELE_Y57G11C.15 Accession_evidence: NDB BX284604
      Public_name: sec-61.A
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Aug 2013 16:41:57 WBPerson2970 Name_change: CGC_name: sec-61
        3 20 May 2019 14:10:26 WBPerson1983 Name_change: CGC_name: sec-61.A
                Other_name: sec-61
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sec
    Allele (56)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (58)
    Structured_description: Automated_description: Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of Sec61 translocon complex. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Is an ortholog of human SEC61A1 (SEC61 translocon subunit alpha 1) and SEC61A2 (SEC61 translocon subunit alpha 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060062 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18276)
  Molecular_info: Corresponding_CDS: Y57G11C.15a
      Y57G11C.15b
    Corresponding_transcript: Y57G11C.15a.1
      Y57G11C.15b.1
    Other_sequence (346)
    Associated_feature (13)
  Experimental_info: RNAi_result: WBRNAi00117219 Inferred_automatically: RNAi_primary
      WBRNAi00000312 Inferred_automatically: RNAi_primary
      WBRNAi00022997 Inferred_automatically: RNAi_primary
      WBRNAi00000220 Inferred_automatically: RNAi_primary
      WBRNAi00085592 Inferred_automatically: RNAi_primary
      WBRNAi00057687 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013952
      Expr1035938
      Expr1161099
      Expr2015719
      Expr2033951
    Drives_construct: WBCnstr00029694
    Construct_product: WBCnstr00029694
    Microarray_results (26)
    Expression_cluster (213)
    Interaction: WBInteraction000034647
      WBInteraction000103659
      WBInteraction000104278
      WBInteraction000104489
      WBInteraction000104519
      WBInteraction000104791
      WBInteraction000104818
      WBInteraction000104836
      WBInteraction000104883
      WBInteraction000105571
      WBInteraction000106346
      WBInteraction000106467
      WBInteraction000107256
      WBInteraction000108795
      WBInteraction000109025
      WBInteraction000109177
      WBInteraction000109377
      WBInteraction000109873
      WBInteraction000109924
      WBInteraction000110166
      WBInteraction000110216
      WBInteraction000110482
      WBInteraction000110491
      WBInteraction000111218
      WBInteraction000112302
      WBInteraction000112609
      WBInteraction000113047
      WBInteraction000113062
      WBInteraction000114429
      WBInteraction000115037
      WBInteraction000120391
      WBInteraction000121506
      WBInteraction000124181
      WBInteraction000137604
      WBInteraction000137911
      WBInteraction000139402
      WBInteraction000140490
      WBInteraction000141474
      WBInteraction000141659
      WBInteraction000145664
      WBInteraction000145762
      WBInteraction000146393
      WBInteraction000146799
      WBInteraction000147360
      WBInteraction000149228
      WBInteraction000149467
      WBInteraction000150261
      WBInteraction000150360
      WBInteraction000150361
      WBInteraction000152087
      WBInteraction000152181
      WBInteraction000152307
      WBInteraction000157756
      WBInteraction000159518
      WBInteraction000160447
      WBInteraction000164633
      WBInteraction000169792
      WBInteraction000169793
      WBInteraction000169794
      WBInteraction000169795
      WBInteraction000169796
      WBInteraction000169797
      WBInteraction000171825
      WBInteraction000175355
      WBInteraction000176115
      WBInteraction000179434
      WBInteraction000181098
      WBInteraction000184447
      WBInteraction000185330
      WBInteraction000185423
      WBInteraction000185424
      WBInteraction000186229
      WBInteraction000188102
      WBInteraction000192513
      WBInteraction000194040
      WBInteraction000194679
      WBInteraction000196132
      WBInteraction000196461
      WBInteraction000197827
      WBInteraction000198591
      WBInteraction000201240
      WBInteraction000201381
      WBInteraction000202523
      WBInteraction000203206
      WBInteraction000216497
      WBInteraction000217178
      WBInteraction000217784
      WBInteraction000219772
      WBInteraction000226509
      WBInteraction000226510
      WBInteraction000232867
      WBInteraction000233940
      WBInteraction000242502
      WBInteraction000242821
      WBInteraction000242898
      WBInteraction000246839
      WBInteraction000255987
      WBInteraction000259147
      WBInteraction000259867
      WBInteraction000261118
      WBInteraction000269454
      WBInteraction000270367
      WBInteraction000270523
      WBInteraction000270524
      WBInteraction000278544
      WBInteraction000281958
      WBInteraction000283931
      WBInteraction000298537
      WBInteraction000298538
      WBInteraction000300153
      WBInteraction000302043
      WBInteraction000302922
      WBInteraction000310203
      WBInteraction000314776
      WBInteraction000315261
      WBInteraction000315987
      WBInteraction000321021
      WBInteraction000321693
      WBInteraction000331510
      WBInteraction000331757
      WBInteraction000331758
      WBInteraction000333065
      WBInteraction000334173
      WBInteraction000336737
      WBInteraction000339528
      WBInteraction000344946
      WBInteraction000352055
      WBInteraction000355817
      WBInteraction000360732
      WBInteraction000371725
      WBInteraction000377435
      WBInteraction000380812
      WBInteraction000398940
      WBInteraction000400281
      WBInteraction000414334
      WBInteraction000421474
      WBInteraction000439181
      WBInteraction000450974
      WBInteraction000463124
      WBInteraction000463296
      WBInteraction000463651
      WBInteraction000464327
      WBInteraction000464887
      WBInteraction000465274
      WBInteraction000465661
      WBInteraction000467295
      WBInteraction000468006
      WBInteraction000468009
      WBInteraction000471320
      WBInteraction000472803
      WBInteraction000472982
      WBInteraction000473171
      WBInteraction000473628
      WBInteraction000474432
      WBInteraction000539743
      WBInteraction000539744
      WBInteraction000540440
      WBInteraction000553034
      WBInteraction000559658
      WBInteraction000562711
      WBInteraction000564270
      WBInteraction000567408
      WBInteraction000570328
      WBInteraction000570741
      WBInteraction000572251
      WBInteraction000572893
      WBInteraction000578322
      WBInteraction000578521
      WBInteraction000580855
      WBInteraction000585884
      WBInteraction000586750
  Map_info: Map: IV Position: 12.5297
    Positive: Positive_clone: Y57G11C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031214
    WBPaper00032322
    WBPaper00033545
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene