WormBase Tree Display for Gene: WBGene00013151
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| WBGene00013151 | SMap | S_parent | Sequence | Y53F4B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | nsun-5 | Paper_evidence | WBPaper00046466 | |||||
| Person_evidence | WBPerson8352 | ||||||||
| Sequence_name | Y53F4B.4 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_Y53F4B.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | nsun-5 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 16 Jan 2006 09:10:17 | WBPerson1983 | Event | Split_into | WBGene00044720 | ||||
| 3 | 20 Feb 2015 13:16:53 | WBPerson2970 | Name_change | CGC_name | nsun-5 | ||||
| Split_into | WBGene00044720 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nsun | ||||||||
| Allele (168) | |||||||||
| Strain | WBStrain00022241 | ||||||||
| WBStrain00037081 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (24) | |||||||||
| Paralog | WBGene00021073 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | nsun-5 is an ortholog of human NSUN5 (NOP2/Sun domain 5); nsun-5 codes for a protein that methylates cytosine 2381 of 26S ribosomal RNA and thereby modulates lifespan and paraquat resistance. | Paper_evidence | WBPaper00046466 | |||||
| Person_evidence | WBPerson29150 | ||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 20 Jun 2016 00:00:00 | ||||||||
| Automated_description | Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of rRNA processing. Predicted to be located in nucleolus. Used to study Williams-Beuren syndrome. Is an ortholog of human NSUN5 (NOP2/Sun RNA methyltransferase 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1928 | Homo sapiens | Paper_evidence | WBPaper00060738 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 26 Aug 2021 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00001018 | ||||||||
| Molecular_info | Corresponding_CDS | Y53F4B.4a | |||||||
| Y53F4B.4b | |||||||||
| Y53F4B.4c | |||||||||
| Corresponding_CDS_history | Y53F4B.4a:wp109 | ||||||||
| Y53F4B.4a:wp153 | |||||||||
| Y53F4B.4b:wp109 | |||||||||
| Corresponding_transcript | Y53F4B.4a.1 | ||||||||
| Y53F4B.4a.2 | |||||||||
| Y53F4B.4a.3 | |||||||||
| Y53F4B.4b.1 | |||||||||
| Y53F4B.4c.1 | |||||||||
| Other_sequence (38) | |||||||||
| Associated_feature | WBsf644878 | ||||||||
| WBsf658450 | |||||||||
| WBsf990868 | |||||||||
| WBsf1013932 | |||||||||
| WBsf222528 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00033276 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00057296 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116278 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020923 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116276 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116277 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076813 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1021904 | ||||||||
| Expr1035840 | |||||||||
| Expr1160731 | |||||||||
| Expr2014505 | |||||||||
| Expr2032744 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (80) | |||||||||
| SAGE_tag | SAGE:gctcgtcttc | Strand | Antisense | ||||||
| SAGE:tcgagaatttgattatt | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:tatgagacacttgttgg | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:ctgttttatt | Strand | Antisense | |||||||
| SAGE:cggttttcct | Strand | Antisense | |||||||
| SAGE:cggcggcaat | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:tatgagacac | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:ttgagtagac | Strand | Antisense | |||||||
| Interaction (206) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | II | Position | 23.8444 | |||||
| Positive | Positive_clone | Y53F4B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00046466 | |||||||||
| WBPaper00049616 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00056642 | |||||||||
| WBPaper00060738 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
