WormBase Tree Display for Gene: WBGene00012977

WBGene00012977 SMap: S_parent: Sequence: Y48A6C
  Identity: Version: 1
    Name: Sequence_name: Y48A6C.4
      Molecular_name: Y48A6C.4
        Y48A6C.4.1
        CE43502
      Other_name: CELE_Y48A6C.4 Accession_evidence: NDB BX284603
      Public_name: Y48A6C.4
    DB_info: Database: AceView gene 3M213
        WormQTL gene WBGene00012977
        WormFlux gene WBGene00012977
        NDB locus_tag CELE_Y48A6C.4
        Panther gene CAEEL|WormBase=WBGene00012977|UniProtKB=Q9XWK5
          family PTHR16056
        NCBI gene 190016
        RefSeq protein NM_067032.4
        TREEFAM TREEFAM_ID TF318197
        TrEMBL UniProtAcc Q9XWK5
        UniProt_GCRP UniProtAcc Q9XWK5
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (96)
    RNASeq_FPKM (74)
    GO_annotation: 00103625
      00103626
      00103627
      00103628
    Ortholog (33)
    Paralog: WBGene00007190 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007786 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009369 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011501 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012976 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00015855 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020070 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: Y48A6C.4 encodes an ortholog of S. cerevisiae IPI1 that may suppress tumorous growth in the germ line by ensuring robust larval germline proliferation; like PRO-1, -2, and -3, Y48A6C.4 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germ line. Paper_evidence: WBPaper00028280
            WBPaper00028929
          Curator_confirmed: WBPerson567
          Date_last_updated: 23 Apr 2008 00:00:00
      Automated_description: Predicted to be located in nucleus. Predicted to be part of MLL1 complex. Is an ortholog of human TEX10 (testis expressed 10). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y48A6C.4
    Corresponding_CDS_history: Y48A6C.4:wp200
    Corresponding_transcript: Y48A6C.4.1
    Other_sequence: GR978404.1
      Hbac_isotig02411
      JI174502.1
      CBC08125_1
      SC00846
      CJC09707_1
      HBC16354_1
      EX914738.1
    Associated_feature: WBsf645601
      WBsf994276
      WBsf994277
      WBsf1015929
      WBsf1015930
      WBsf225794
      WBsf225795
  Experimental_info: RNAi_result: WBRNAi00006365 Inferred_automatically: RNAi_primary
      WBRNAi00009350 Inferred_automatically: RNAi_primary
      WBRNAi00026750 Inferred_automatically: RNAi_primary
      WBRNAi00071666 Inferred_automatically: RNAi_primary
      WBRNAi00071364 Inferred_automatically: RNAi_primary
      WBRNAi00002637 Inferred_automatically: RNAi_primary
      WBRNAi00056871 Inferred_automatically: RNAi_primary
      WBRNAi00037226 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021678
      Expr1035755
      Expr1160323
      Expr2007653
      Expr2025893
    Microarray_results (22)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059987:Wounding_downregulated
      WBPaper00061340:AIZ
      WBPaper00061340:B
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061466:nath-10(icb99)_downregulated
      WBPaper00061527:Y39G10AR.18_4775-gld-4
      WBPaper00061902:CAMT-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00064735:bet-1B(OE)mys-1(RNAi)_vs_mys-1(RNAi)_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_7
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00037695:WC_5-day
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_3h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_downregulated
    Interaction: WBInteraction000040356
      WBInteraction000044341
      WBInteraction000044345
      WBInteraction000044354
      WBInteraction000044359
      WBInteraction000046099
      WBInteraction000048561
      WBInteraction000240606
      WBInteraction000297044
  Map_info: Positive: Positive_clone: Y48A6C Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III 6.07936
  Reference: WBPaper00028280
    WBPaper00038491
    WBPaper00055090
  Method: Gene