WormBase Tree Display for Gene: WBGene00012769
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| WBGene00012769 | SMap | S_parent | Sequence | Y41E3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | hrpu-1 | Person_evidence | WBPerson2799 | |||||
| Sequence_name | Y41E3.11 | ||||||||
| Molecular_name (14) | |||||||||
| Other_name | CELE_Y41E3.11 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | hrpu-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Jan 2009 16:18:10 | WBPerson4055 | Event | Acquires_merge | WBGene00012774 | ||||
| 3 | 16 Feb 2017 15:37:28 | WBPerson2970 | Name_change | CGC_name | hrpu-1 | ||||
| Acquires_merge | WBGene00012774 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hrpu | ||||||||
| Allele (205) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Contained_in_operon | CEOP4685 | ||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00017620 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00008035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Automated_description | Enriched in several structures, including AVE; germ line; mechanosensory neurons; rectal epithelial cell; and rectum based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including aldicarb; rotenone; and Cry5B based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in colorectal cancer and developmental and epileptic encephalopathy 54. Human HNRNPU enables several functions, including ATP binding activity; basal RNA polymerase II transcription machinery binding activity; and nucleic acid binding activity. Is predicted to encode a protein with the following domains: B30.2/SPRY domain superfamily; SPRY domain; Concanavalin A-like lectin/glucanase domain superfamily; P-loop containing nucleoside triphosphate hydrolase; and AAA domain. Is an ortholog of human HNRNPU (heterogeneous nuclear ribonucleoprotein U) and HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U like 2). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5048) | ||||
| DOID:0080418 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5048) | ||||||
| Molecular_info | Corresponding_CDS | Y41E3.11a | |||||||
| Y41E3.11b | |||||||||
| Y41E3.11c | |||||||||
| Y41E3.11d | |||||||||
| Corresponding_transcript | Y41E3.11e | ||||||||
| Y41E3.11a.1 | |||||||||
| Y41E3.11a.2 | |||||||||
| Y41E3.11b.1 | |||||||||
| Y41E3.11c.1 | |||||||||
| Y41E3.11d.1 | |||||||||
| Other_sequence | PPC13226_1 | ||||||||
| JO470638.1 | |||||||||
| Oden_isotig18713 | |||||||||
| CRC11320_1 | |||||||||
| JI475266.1 | |||||||||
| HG07867 | |||||||||
| HGC04318_1 | |||||||||
| Acan_isotig22626 | |||||||||
| JI164039.1 | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr1026223 | ||||||||
| Expr1035651 | |||||||||
| Expr1159886 | |||||||||
| Expr2012604 | |||||||||
| Expr2030840 | |||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (121) | |||||||||
| Interaction (176) | |||||||||
| Map_info | Positive | Positive_clone | Y41E3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | IV | 12.8204 | |||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00052934 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
