Y39B6A.33 encodes the C. elegans ortholog of mammalian GLTSCR2/PICT1 (GLioma Tumor Suppressor Candidate Region gene 2/Protein Interacting with the C Terminus-1); loss of Y39B6A.33 activity via RNAi results in lower oxygen consumption rates, suggesting that Y39B6A.33 plays a role in positively regulating mitochondrial respiration rates; in body wall muscle cells, Y39B6A.33 localizes to the nucleolus.
Predicted to enable 5S rRNA binding activity. Involved in positive regulation of cellular respiration. Located in nucleolus. Is an ortholog of human NOP53 (NOP53 ribosome biogenesis factor).