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WormBase Tree Display for Gene: WBGene00012186

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Name Class

WBGene00012186SMapS_parentSequenceW01F3
IdentityVersion3
NameCGC_namemlt-11Person_evidenceWBPerson545
WBPerson3379
Sequence_nameW01F3.3
Molecular_name (24)
Other_namephi-36Person_evidenceWBPerson2582
CELE_W01F3.3Accession_evidenceNDBBX284605
Public_namemlt-11
DB_infoDatabaseAceViewgene5V147
WormQTLgeneWBGene00012186
WormFluxgeneWBGene00012186
NDBlocus_tagCELE_W01F3.3
PanthergeneCAEEL|WormBase=WBGene00012186|UniProtKB=B9WRT9
familyPTHR10083
NCBIgene180352
RefSeqproteinNM_001270012.3
NM_001270011.3
NM_001270009.3
NM_001270014.3
NM_001270015.4
NM_001270013.3
NM_001270016.3
NM_001270010.3
TREEFAMTREEFAM_IDTF315349
TrEMBLUniProtAccO45881
C1P660
C1P659
B9WRT9
H9G334
H9G335
H9G336
C1P658
UniProt_GCRPUniProtAccB9WRT9
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
217 Mar 2005 13:54:35WBPerson2970Name_changeOther_namephi-36
328 Jul 2005 14:22:15WBPerson2970Name_changeCGC_namemlt-11
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmlt
Allele (211)
RNASeq_FPKM (74)
GO_annotation00006591
00006592
00006593
00006594
00119363
Ortholog (29)
Paralog (28)
Structured_descriptionConcise_descriptionmlt-11 encodes one of 13 C. elegans proteins related to the mammalian Tissue Factor Pathway Inhibitors (TFPIs), serine protease inhibitors that function in blood coagulation (OMIM:152310); in C. elegans, genetic analysis indicates that mlt-11 is required for proper molting and, likely, for proper spatial and/or temporal regulation of proteolysis during the molting cycle; a mlt-11::gfp promoter fusion is expressed mid-way through each larval stage in the hypodermis including the hyp7 syncytium, the lateral seam cells (at larval-to-larval molts) and head and tail hypodermis; mlt-11 expression appears to be positively regulated by NHR-23 and LIN-14.Paper_evidenceWBPaper00026763
WBPaper00026952
Curator_confirmedWBPerson1843
Date_last_updated22 Jan 2009 00:00:00
Automated_descriptionPredicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Expressed in hypodermis.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSW01F3.3a
W01F3.3b
W01F3.3c
W01F3.3d
W01F3.3e
W01F3.3f
W01F3.3g
W01F3.3h
Corresponding_CDS_historyW01F3.3:wp158
Corresponding_transcriptW01F3.3a.1
W01F3.3b.1
W01F3.3c.1
W01F3.3d.1
W01F3.3e.1
W01F3.3f.1
W01F3.3g.1
W01F3.3h.1
Other_sequence (47)
Associated_feature (23)
Experimental_infoRNAi_resultWBRNAi00066552Inferred_automaticallyRNAi_primary
WBRNAi00089175Inferred_automaticallyRNAi_primary
WBRNAi00095752Inferred_automaticallyRNAi_primary
WBRNAi00026446Inferred_automaticallyRNAi_primary
WBRNAi00054530Inferred_automaticallyRNAi_primary
WBRNAi00065007Inferred_automaticallyRNAi_primary
WBRNAi00066817Inferred_automaticallyRNAi_primary
WBRNAi00009240Inferred_automaticallyRNAi_primary
WBRNAi00066739Inferred_automaticallyRNAi_primary
Expr_patternExpr3693
Expr1011804
Expr1035388
Expr1158076
Expr2013605
Expr2031838
Drives_constructWBCnstr00006890
WBCnstr00011604
WBCnstr00030076
Construct_productWBCnstr00030076
Microarray_results (28)
Expression_cluster (337)
Interaction (81)
Map_infoMapVPosition25.031Error0.000443
PositivePositive_cloneW01F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026952
WBPaper00038491
WBPaper00055090
WBPaper00059378
WBPaper00061662
WBPaper00062278
WBPaper00062715
WBPaper00062969
WBPaper00065000
WBPaper00065560
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene