WormBase Tree Display for Gene: WBGene00012148
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| WBGene00012148 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | inos-1 | Person_evidence | WBPerson9275 | |||||
| Sequence_name | VF13D12L.1 | ||||||||
| Molecular_name | VF13D12L.1 | ||||||||
| VF13D12L.1.1 | |||||||||
| CE31076 | |||||||||
| Other_name | CELE_VF13D12L.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | inos-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 05 May 2011 12:15:34 | WBPerson2970 | Name_change | CGC_name | inos-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | inos | ||||||||
| Allele | WBVar00770757 | ||||||||
| WBVar00770758 | |||||||||
| WBVar00770759 | |||||||||
| WBVar01499702 | |||||||||
| WBVar00770760 | |||||||||
| WBVar00770761 | |||||||||
| WBVar00770762 | |||||||||
| WBVar00770763 | |||||||||
| WBVar00770764 | |||||||||
| WBVar00770765 | |||||||||
| WBVar00770766 | |||||||||
| WBVar00770767 | |||||||||
| WBVar00770768 | |||||||||
| WBVar00770769 | |||||||||
| WBVar00770770 | |||||||||
| WBVar01498613 | |||||||||
| WBVar01498435 | |||||||||
| WBVar02130766 | |||||||||
| WBVar00229778 | |||||||||
| WBVar00311007 | |||||||||
| WBVar01766431 | |||||||||
| WBVar01766432 | |||||||||
| WBVar02146950 | |||||||||
| WBVar02146951 | |||||||||
| WBVar00378935 | |||||||||
| WBVar00378936 | |||||||||
| WBVar00378937 | |||||||||
| WBVar00378938 | |||||||||
| WBVar01498941 | |||||||||
| WBVar01605131 | |||||||||
| WBVar00770748 | |||||||||
| WBVar00770749 | |||||||||
| WBVar00770750 | |||||||||
| WBVar00770751 | |||||||||
| WBVar00770752 | |||||||||
| WBVar00770753 | |||||||||
| WBVar00770754 | |||||||||
| WBVar00770755 | |||||||||
| WBVar00770756 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | inos-1 encodes the C. elegans myo-inositol-1-phosphate (MIP) synthase ortholog; by homology, the product of inos-1 is predicted to function in de novo inositol biosynthesis by catalyzing the conversion of glucose-6-phosphate to inositol-1-phosphate; loss of inos-1 activity via RNAi has been reported to result in low levels of embryonic lethality, larval lethality, slow growth, uncoordinated locomotion, and a substantial increase in fat content; loss of inos-1 activity also results in a slight increase in the variability of the defecation cycle length, although this increase is not statistically significant; in situ hybridization studies reveal that inos-1 mRNA is expressed faintly in the germline. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00005655 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00027758 | |||||||||
| WBPaper00031535 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 05 May 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable inositol-3-phosphate synthase activity. Predicted to be involved in inositol biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Is an ortholog of human ISYNA1 (inositol-3-phosphate synthase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | VF13D12L.1 | |||||||
| Corresponding_transcript | VF13D12L.1.1 | ||||||||
| Other_sequence (81) | |||||||||
| Associated_feature | WBsf650614 | ||||||||
| WBsf650615 | |||||||||
| WBsf650616 | |||||||||
| WBsf666190 | |||||||||
| WBsf666191 | |||||||||
| WBsf989857 | |||||||||
| WBsf223984 | |||||||||
| Experimental_info | RNAi_result (8) | ||||||||
| Expr_pattern | Expr4091 | ||||||||
| Expr1023077 | |||||||||
| Expr1035373 | |||||||||
| Expr1158012 | |||||||||
| Expr2012744 | |||||||||
| Expr2030981 | |||||||||
| Drives_construct | WBCnstr00030104 | ||||||||
| Construct_product | WBCnstr00030104 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (148) | |||||||||
| Interaction (76) | |||||||||
| Map_info | Map | II | Position | 3.99091 | Error | 0.005099 | |||
| Positive | Positive_clone | VF13D12L | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00019539 | ||||||||
| WBPaper00031535 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
