WormBase Tree Display for Gene: WBGene00011966

WBGene00011966 SMap: S_parent: Sequence: T23G7
  Identity: Version: 1
    Name: Sequence_name: T23G7.3
      Molecular_name: T23G7.3
        T23G7.3.1
        CE03704
      Other_name: CELE_T23G7.3 Accession_evidence: NDB BX284602
      Public_name: T23G7.3
    DB_info: Database: AceView gene 2J456
        WormQTL gene WBGene00011966
        WormFlux gene WBGene00011966
        NDB locus_tag CELE_T23G7.3
        Panther gene CAEEL|WormBase=WBGene00011966|UniProtKB=Q22705
          family PTHR23149
        NCBI gene 174456
        RefSeq protein NM_063554.7
        TREEFAM TREEFAM_ID TF321918
        TrEMBL UniProtAcc Q22705
        UniProt_GCRP UniProtAcc Q22705
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (34)
    RNASeq_FPKM (74)
    GO_annotation: 00076086
      00076087
      00119168
    Contained_in_operon: CEOP2416
    Ortholog (32)
    Structured_description: Automated_description: Predicted to enable telomerase inhibitor activity. Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:30046)
  Molecular_info: Corresponding_CDS: T23G7.3
    Corresponding_transcript: T23G7.3.1
    Other_sequence (49)
    Associated_feature: WBsf1012820
      WBsf223609
  Experimental_info: RNAi_result: WBRNAi00019110 Inferred_automatically: RNAi_primary
      WBRNAi00035892 Inferred_automatically: RNAi_primary
      WBRNAi00000967 Inferred_automatically: RNAi_primary
      WBRNAi00053983 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013140
      Expr1035284
      Expr1157528
      Expr2006428
      Expr2024648
    Drives_construct: WBCnstr00030243
    Construct_product: WBCnstr00030243
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032425:down_in_alg-1
      WBPaper00032425:down_in_zfp-1
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:AVA-neuron_embryo_enriched
      WBPaper00037950:bodywall-muscle_CoreEnriched
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:coelomocytes_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_CoreEnriched
      WBPaper00037950:dopaminergic-neurons_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_embryo_enriched
      WBPaper00037950:glr-1(+)-neurons_larva_enriched
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044557:DietaryRestriction_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046795:starvation_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049290:rsks-1(sv31)_downregulated
      WBPaper00049368:daf-2(e1370)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00051257:Levamisole_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00054758:alg-2(ok304)_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056617:adr-1(tm668)_downregulated_L4_protein
      WBPaper00056826:SGP_biased
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057083:daf-2(e1370)rsks-1(ok1255)_post-transcriptional_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:F49E2.5_8378-anc-1_2769
      WBPaper00061651:CAN_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062095:unc-4(e120)_upregulated_VA-neuron
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062606:rotenone_upregulated
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064952:Day10_vs_L4_downregulated_20C
      WBPaper00064952:Day10_vs_L4_downregulated_25C
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00005124:testosterone_10-9M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_E
      WBPaper00026980:intestine_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:StarveUp4
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036286:Pattern_B
      WBPaper00037147:heatshock_upregulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00041207:CE_dauer_up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:daf-16_fasting_upregulated
      WBPaper00041960:jun-1_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048624:hlh-25(ok1710)_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecalis_upregulated
      WBPaper00053688:E.faecium_upregulated
      [cgc5767]:cluster_61
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(66_min)
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc5976]:class_1
      [cgc6390]:herm_sex-enriched
    Interaction (182)
  Map_info: Positive: Positive_clone: T23G7 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II 1.06927
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00065841
  Method: Gene