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WormBase Tree Display for Gene: WBGene00011884

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Name Class

WBGene00011884SMapS_parentSequenceT21B10
IdentityVersion2
NameCGC_nameenol-1Person_evidenceWBPerson1818
Sequence_nameT21B10.2
Molecular_nameT21B10.2a
T21B10.2a.1
CE03684
T21B10.2c
CE36954
T21B10.2a.2
T21B10.2c.1
Other_nameCELE_T21B10.2Accession_evidenceNDBBX284602
Public_nameenol-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
227 Apr 2006 11:26:11WBPerson2970Name_changeCGC_nameenol-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classenol
Allele (50)
StrainWBStrain00001714
WBStrain00032423
RNASeq_FPKM (74)
GO_annotation (16)
Contained_in_operonCEOP2749
Ortholog (53)
Structured_descriptionConcise_descriptionenol-1 is orthologous to human ENOLASE 1 (also CRYSTALLIN, TAU; ENO1; OMIM:172430), which when mutated leads to spherocytic red cell enolase deficiency.Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated05 Oct 2009 00:00:00
Automated_descriptionPredicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to be located in cytoplasm. Predicted to be part of phosphopyruvate hydratase complex. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; migraine without aura; neuroendocrine carcinoma; and prostate cancer. Is an ortholog of human ENO2 (enolase 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3350)
DOID:11054Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
DOID:12783Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
DOID:3459Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
DOID:10763Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
DOID:1800Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
DOID:10283Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
DOID:936Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3353)
EFO:MONDO:0002412Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3354)
Molecular_infoCorresponding_CDST21B10.2a
T21B10.2c
Corresponding_CDS_historyT21B10.2b:wp261
Corresponding_transcriptT21B10.2a.1
T21B10.2a.2
T21B10.2c.1
Other_sequence (387)
Associated_feature (14)
Experimental_infoRNAi_result (15)
Expr_patternChronogram543
Expr6726
Expr1017468
Expr1035236
Expr1157236
Expr2011319
Expr2029555
Drives_constructWBCnstr00002538
WBCnstr00030312
Construct_productWBCnstr00030312
Microarray_results (44)
Expression_cluster (199)
SAGE_tag (14)
Interaction (176)
Map_infoMapIIPosition0.93367Error0.000865
PositivePositive_cloneT21B10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027145
WBPaper00028498
WBPaper00028807
WBPaper00031648
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00056474
WBPaper00062642
WBPaper00064933
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene