WormBase Tree Display for Gene: WBGene00011771
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| WBGene00011771 | SMap | S_parent | Sequence | T14G8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | T14G8.3 | |||||||
| Molecular_name | T14G8.3 | ||||||||
| T14G8.3.1 | |||||||||
| CE37407 | |||||||||
| Other_name | CELE_T14G8.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | T14G8.3 | ||||||||
| DB_info | Database | AceView | gene | XN487 | |||||
| WormQTL | gene | WBGene00011771 | |||||||
| WormFlux | gene | WBGene00011771 | |||||||
| NDB | locus_tag | CELE_T14G8.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011771|UniProtKB=Q22515 | |||||||
| family | PTHR45639 | ||||||||
| NCBI | gene | 181422 | |||||||
| RefSeq | protein | NM_001029742.7 | |||||||
| TrEMBL | UniProtAcc | Q22515 | |||||||
| UniProt_GCRP | UniProtAcc | Q22515 | |||||||
| OMIM | gene | 601746 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (142) | |||||||||
| Strain | WBStrain00031455 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00075469 | ||||||||
| 00075470 | |||||||||
| 00075471 | |||||||||
| 00075472 | |||||||||
| 00075473 | |||||||||
| 00075474 | |||||||||
| 00075475 | |||||||||
| 00105757 | |||||||||
| 00119003 | |||||||||
| 00119004 | |||||||||
| Ortholog (43) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | T14G8.3 encodes an ortholog of hypoxia-upregulated vertebrate proteins such as human HYOU1; T14G8.3, its C. elegans paralog T24H7.2, and HYOU1 are ER resident hsp70 family molecular chaperone homologs; the grp (glucose regulated protein) 170 family is a collection of related large hsp70 chaperones confined to the ER; members of this family are present in all eukaryotes, participating in a wide range of cellular functions. | Paper_evidence | WBPaper00028288 | |||||
| WBPaper00028291 | |||||||||
| WBPaper00028319 | |||||||||
| WBPaper00028321 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 18 Jul 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable adenyl-nucleotide exchange factor activity. Involved in IRE1-mediated unfolded protein response. Predicted to be part of endoplasmic reticulum chaperone complex. Human ortholog(s) of this gene implicated in immunodeficiency 59. Is an ortholog of human HYOU1 (hypoxia up-regulated 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111974 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16931) | ||||
| Molecular_info | Corresponding_CDS | T14G8.3 | |||||||
| Corresponding_CDS_history | T14G8.3:wp131 | ||||||||
| T14G8.3b:wp272 | |||||||||
| Corresponding_transcript | T14G8.3.1 | ||||||||
| Other_sequence (35) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00076679 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00001906 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106355 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035582 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000500 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00053347 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00018730 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1026039 | ||||||||
| Expr1035184 | |||||||||
| Expr1156932 | |||||||||
| Expr2006184 | |||||||||
| Expr2024400 | |||||||||
| Drives_construct | WBCnstr00030402 | ||||||||
| Construct_product | WBCnstr00030402 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (172) | |||||||||
| Interaction (56) | |||||||||
| Map_info | Positive | Positive_clone | T14G8 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | X | 8.66255 | |||||||
| Reference | WBPaper00005432 | ||||||||
| WBPaper00026830 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041022 | |||||||||
| WBPaper00051015 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
