WormBase Tree Display for Gene: WBGene00011676
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WBGene00011676 | SMap | S_parent | Sequence | T10B9 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cyp-13A2 | |||||||
Sequence_name | T10B9.7 | ||||||||
Molecular_name | T10B9.7 | ||||||||
T10B9.7.1 | |||||||||
CE01659 | |||||||||
Other_name | CELE_T10B9.7 | Accession_evidence | NDB | BX284602 | |||||
Public_name | cyp-13A2 | ||||||||
DB_info | Database | AceView | gene | 2K74 | |||||
WormQTL | gene | WBGene00011676 | |||||||
WormFlux | gene | WBGene00011676 | |||||||
NDB | locus_tag | CELE_T10B9.7 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00011676|UniProtKB=Q27518 | |||||||
family | PTHR24282 | ||||||||
NCBI | gene | 188360 | |||||||
RefSeq | protein | NM_063708.5 | |||||||
KEGG | KEGG_id | 1.14.-.- | |||||||
NemaPath | KEGG_id | 1.14.-.- | |||||||
SwissProt | UniProtAcc | Q27518 | |||||||
TREEFAM | TREEFAM_ID | TF352036 | |||||||
UniProt_GCRP | UniProtAcc | Q27518 | |||||||
OMIM | gene | 274180 | |||||||
605325 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-13A2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cyp | ||||||||
Allele (68) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00079959 | ||||||||
00079960 | |||||||||
00079961 | |||||||||
00118915 | |||||||||
00118916 | |||||||||
00118917 | |||||||||
00118918 | |||||||||
Contained_in_operon | CEOP2766 | ||||||||
Ortholog (80) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | cyp-13A2 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
Molecular_info | Corresponding_CDS | T10B9.7 | |||||||
Corresponding_transcript | T10B9.7.1 | ||||||||
Other_sequence (11) | |||||||||
Associated_feature | WBsf650458 | ||||||||
WBsf650459 | |||||||||
WBsf989147 | |||||||||
WBsf989148 | |||||||||
WBsf1012903 | |||||||||
WBsf1012904 | |||||||||
Experimental_info | RNAi_result | WBRNAi00035425 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092621 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00018528 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00053020 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1025189 | ||||||||
Expr1156620 | |||||||||
Expr2010682 | |||||||||
Expr2028922 | |||||||||
Drives_construct | WBCnstr00030477 | ||||||||
Construct_product | WBCnstr00030477 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (232) | |||||||||
Interaction | WBInteraction000029615 | ||||||||
WBInteraction000123286 | |||||||||
WBInteraction000123362 | |||||||||
WBInteraction000123363 | |||||||||
WBInteraction000123364 | |||||||||
WBInteraction000123490 | |||||||||
WBInteraction000123533 | |||||||||
WBInteraction000123579 | |||||||||
WBInteraction000123606 | |||||||||
WBInteraction000123634 | |||||||||
WBInteraction000123666 | |||||||||
WBInteraction000123734 | |||||||||
WBInteraction000123754 | |||||||||
WBInteraction000123773 | |||||||||
WBInteraction000123791 | |||||||||
WBInteraction000123808 | |||||||||
WBInteraction000123824 | |||||||||
WBInteraction000123882 | |||||||||
WBInteraction000174302 | |||||||||
WBInteraction000174450 | |||||||||
WBInteraction000286494 | |||||||||
WBInteraction000309162 | |||||||||
WBInteraction000340730 | |||||||||
WBInteraction000341125 | |||||||||
WBInteraction000416877 | |||||||||
WBInteraction000436770 | |||||||||
WBInteraction000469948 | |||||||||
WBInteraction000585603 | |||||||||
Map_info | Map | II | Position | 1.71406 | Error | 0.000287 | |||
Positive | Positive_clone | T10B9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00026952 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00042257 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00064598 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |