WormBase Tree Display for Gene: WBGene00011672
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WBGene00011672 | SMap | S_parent | Sequence | T10B9 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cyp | ||||||
Allele (36) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00079947 | ||||||
00079948 | |||||||
00079949 | |||||||
00118899 | |||||||
00118900 | |||||||
00118901 | |||||||
00118902 | |||||||
Ortholog (64) | |||||||
Paralog (12) | |||||||
Structured_description | Concise_description | cyp-13A5 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates; loss of cyp-13A5 activity in large-scale RNAi screens results in uncoordinated locomotion, decreased and/or slow growth, and cadmium hypersensitivity. | Paper_evidence | WBPaper00005654 | |||
WBPaper00006395 | |||||||
WBPaper00030811 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 20 Nov 2008 00:00:00 | ||||||
Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||
DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||
DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||
DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||
Molecular_info | Corresponding_CDS | T10B9.2 | |||||
Corresponding_transcript | T10B9.2.1 | ||||||
Other_sequence | JI174138.1 | ||||||
Oden_isotig14710 | |||||||
Acan_isotig21796 | |||||||
Associated_feature | WBsf223709 | ||||||
WBsf223710 | |||||||
Experimental_info | RNAi_result | WBRNAi00018525 | Inferred_automatically | RNAi_primary | |||
WBRNAi00070152 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00053015 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00035421 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092623 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1156616 | ||||||
Expr2010685 | |||||||
Expr2028924 | |||||||
Drives_construct | WBCnstr00030481 | ||||||
Construct_product | WBCnstr00030481 | ||||||
Microarray_results (14) | |||||||
Expression_cluster (327) | |||||||
Interaction (36) | |||||||
Map_info | Map | II | Position | 1.7164 | Error | 0.000227 | |
Positive | Positive_clone | T10B9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00037579 | ||||||
WBPaper00038491 | |||||||
WBPaper00042257 | |||||||
WBPaper00055090 | |||||||
WBPaper00064073 | |||||||
WBPaper00064598 | |||||||
WBPaper00065331 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |