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WormBase Tree Display for Gene: WBGene00011580

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Name Class

WBGene00011580SMapS_parentSequenceCHROMOSOME_II
IdentityVersion2
NameCGC_nameddx-19Person_evidenceWBPerson555
WBPerson3232
Sequence_nameT07D4.4
Molecular_name (15)
Other_nameCELE_T07D4.4Accession_evidenceNDBBX284602
Public_nameddx-19
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
220 Feb 2008 16:59:39WBPerson2970Name_changeCGC_nameddx-19
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classddx
Allele (58)
StrainWBStrain00003226
WBStrain00031624
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (48)
Paralog (37)
Structured_descriptionConcise_descriptionddx-19 encodes a DEAD-box helicase; ddx-19(RNAi) in a mpk-1(ga111ts) mutant background results in germline developmental defects, including disruption of membrane organization in pachytene cells and disorganized oocytes; DDX-19 can be phosphorylated by murine ERK2 in vitro, suggesting that it is a substrate for the RTK-RAS-ERK pathway in vivo; consistent with this, DDX-19 phosphorylation is absent in mpk-1 mutant animals; DDX-19 localizes to perinuclear P granules.Paper_evidenceWBPaper00031057
WBPaper00032961
WBPaper00036048
Curator_confirmedWBPerson1843
Date_last_updated23 Jan 2012 00:00:00
Automated_descriptionPredicted to enable RNA binding activity and RNA helicase activity. Involved in germ cell development. Located in P granule. Expressed in tail. Is an ortholog of human DDX19A (DEAD-box helicase 19A) and DDX19B (DEAD-box helicase 19B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST07D4.4a
T07D4.4b
T07D4.4c
T07D4.4d
T07D4.4e
Corresponding_transcriptT07D4.4a.1
T07D4.4b.1
T07D4.4c.1
T07D4.4d.1
T07D4.4e.1
Other_sequence (50)
Associated_feature (19)
Experimental_infoRNAi_resultWBRNAi00018369Inferred_automaticallyRNAi_primary
WBRNAi00052760Inferred_automaticallyRNAi_primary
WBRNAi00075465Inferred_automaticallyRNAi_primary
Expr_patternChronogram2084
Expr6629
Expr9012
Expr1010235
Expr1035104
Expr1156369
Expr2010835
Expr2029073
Drives_constructWBCnstr00003701
WBCnstr00030544
Construct_productWBCnstr00030544
AntibodyWBAntibody00002132
Microarray_results (39)
Expression_cluster (133)
Interaction (113)
Map_infoMapIIPosition0.92188Error0.002109
PositivePositive_cloneT07D4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00030647
WBPaper00032961
WBPaper00036048
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene