WormBase Tree Display for Gene: WBGene00011398
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| WBGene00011398 | SMap | S_parent | Sequence | T03F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | qdpr-1 | Person_evidence | WBPerson384 | |||||
| Sequence_name | T03F6.1 | ||||||||
| Molecular_name | T03F6.1 | ||||||||
| T03F6.1.1 | |||||||||
| CE16335 | |||||||||
| Other_name | CELE_T03F6.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | qdpr-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 28 Sep 2005 14:42:19 | WBPerson2970 | Name_change | CGC_name | qdpr-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | qdpr | ||||||||
| Allele (21) | |||||||||
| Strain | WBStrain00024117 | ||||||||
| WBStrain00024118 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00102545 | ||||||||
| 00102546 | |||||||||
| 00102547 | |||||||||
| 00102548 | |||||||||
| 00102549 | |||||||||
| 00102550 | |||||||||
| 00102551 | |||||||||
| 00102552 | |||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | The T03F6.1 gene encodes an ortholog of the human gene QUINOID DIHYDROPTERIDINE REDUCTASE (QDPR; DHPR), which when mutated leads to phenylketonuria II (OMIM:261630). | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable 6,7-dihydropteridine reductase activity; NADH binding activity; and NADPH binding activity. Predicted to be involved in L-phenylalanine catabolic process and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytoplasm. Expressed in several structures, including CEP; gonad; hypodermis; serotonergic neurons; and tail. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia C and phenylketonuria. Is an ortholog of human QDPR (quinoid dihydropteridine reductase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0081130 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9752) | ||||
| DOID:9281 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9752) | ||||||
| Molecular_info | Corresponding_CDS | T03F6.1 | |||||||
| Corresponding_transcript | T03F6.1.1 | ||||||||
| Other_sequence (56) | |||||||||
| Associated_feature | WBsf645709 | ||||||||
| WBsf994875 | |||||||||
| WBsf1016363 | |||||||||
| WBsf226000 | |||||||||
| WBsf226001 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00006277 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00052289 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006916 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035099 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00018078 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044398 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11444 | ||||||||
| Expr12168 | |||||||||
| Expr13109 | |||||||||
| Expr1015613 | |||||||||
| Expr1035014 | |||||||||
| Expr1155920 | |||||||||
| Expr2015209 | |||||||||
| Expr2033443 | |||||||||
| Drives_construct | WBCnstr00020339 | ||||||||
| WBCnstr00020340 | |||||||||
| WBCnstr00020347 | |||||||||
| WBCnstr00030688 | |||||||||
| Construct_product | WBCnstr00020340 | ||||||||
| WBCnstr00030688 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (156) | |||||||||
| Interaction (53) | |||||||||
| Map_info | Map | III | Position | 21.213 | Error | 4.5e-05 | |||
| Positive | Positive_clone | T03F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00034518 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00046585 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
