WormBase Tree Display for Gene: WBGene00011398

WBGene00011398 SMap: S_parent: Sequence: T03F6
  Identity: Version: 2
    Name: CGC_name: qdpr-1 Person_evidence: WBPerson384
      Sequence_name: T03F6.1
      Molecular_name: T03F6.1
        T03F6.1.1
        CE16335
      Other_name: CELE_T03F6.1 Accession_evidence: NDB BX284603
      Public_name: qdpr-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 28 Sep 2005 14:42:19 WBPerson2970 Name_change: CGC_name: qdpr-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: qdpr
    Allele (21)
    Strain: WBStrain00024117
      WBStrain00024118
    RNASeq_FPKM (74)
    GO_annotation: 00102545
      00102546
      00102547
      00102548
      00102549
      00102550
      00102551
      00102552
    Ortholog: WBGene00064211 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00029210 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00162664 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00101428 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00129031 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00225774 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g6467 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g4424 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g17337 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g861 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g18294 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g17531 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g25701 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g2058 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP32.g899 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6501 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g3975 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g21320 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g24107 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_01348.g16280 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_10507.g22690 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-qdpr-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold605.g5633 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00662.g14164 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_00801.g15575 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_12290 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_23585 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_007963 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02368 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g23357 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30020800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g9339 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00247038 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00259793 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00286041 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0035964 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080219-12 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-070705-197 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050522-320 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-070720-19 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:9752 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:97836 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:619915 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: The T03F6.1 gene encodes an ortholog of the human gene QUINOID DIHYDROPTERIDINE REDUCTASE (QDPR; DHPR), which when mutated leads to phenylketonuria II (OMIM:261630). Paper_evidence: WBPaper00004637
          Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable 6,7-dihydropteridine reductase activity; NADH binding activity; and NADPH binding activity. Predicted to be involved in L-phenylalanine catabolic process and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytoplasm. Expressed in several structures, including CEP; gonad; hypodermis; serotonergic neurons; and tail. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia C and phenylketonuria. Is an ortholog of human QDPR (quinoid dihydropteridine reductase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0081130 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9752)
      DOID:9281 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9752)
  Molecular_info: Corresponding_CDS: T03F6.1
    Corresponding_transcript: T03F6.1.1
    Other_sequence (56)
    Associated_feature: WBsf645709
      WBsf994875
      WBsf1016363
      WBsf226000
      WBsf226001
  Experimental_info: RNAi_result: WBRNAi00006277 Inferred_automatically: RNAi_primary
      WBRNAi00052289 Inferred_automatically: RNAi_primary
      WBRNAi00006916 Inferred_automatically: RNAi_primary
      WBRNAi00035099 Inferred_automatically: RNAi_primary
      WBRNAi00018078 Inferred_automatically: RNAi_primary
      WBRNAi00044398 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11444
      Expr12168
      Expr13109
      Expr1015613
      Expr1035014
      Expr1155920
      Expr2015209
      Expr2033443
    Drives_construct: WBCnstr00020339
      WBCnstr00020340
      WBCnstr00020347
      WBCnstr00030688
    Construct_product: WBCnstr00020340
      WBCnstr00030688
    Microarray_results (20)
    Expression_cluster (156)
    Interaction (53)
  Map_info: Map: III Position: 21.213 Error: 4.5e-05
    Positive: Positive_clone: T03F6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00034518
    WBPaper00038491
    WBPaper00046585
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene