WormBase Tree Display for Gene: WBGene00010705
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| WBGene00010705 | SMap | S_parent | Sequence | K09A11 | ||
|---|---|---|---|---|---|---|
| Identity (6) | ||||||
| Gene_info | Biotype | SO:0001217 | ||||
| Gene_class | cyp | |||||
| Allele (45) | ||||||
| RNASeq_FPKM (74) | ||||||
| GO_annotation | 00079911 | |||||
| 00079912 | ||||||
| 00079913 | ||||||
| 00079914 | ||||||
| 00118047 | ||||||
| 00118048 | ||||||
| 00118049 | ||||||
| 00118050 | ||||||
| Ortholog (55) | ||||||
| Paralog (42) | ||||||
| Structured_description | Concise_description | cyp-14A1 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Curator_confirmed | WBPerson1843 | ||
| Date_last_updated | 20 Nov 2008 00:00:00 | |||||
| Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). | Paper_evidence | WBPaper00065943 | |||
| Curator_confirmed | WBPerson324 | |||||
| WBPerson37462 | ||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
| Date_last_updated | 29 Nov 2023 00:00:00 | |||||
| Disease_info | Potential_model (12) | |||||
| Molecular_info | Corresponding_CDS | K09A11.2 | ||||
| Corresponding_transcript | K09A11.2.1 | |||||
| Other_sequence | EY468469.1 | |||||
| PPC09763_1 | ||||||
| Associated_feature | WBsf982263 | |||||
| WBsf238117 | ||||||
| Experimental_info | RNAi_result | WBRNAi00050360 | Inferred_automatically | RNAi_primary | ||
| WBRNAi00034174 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00092632 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00116299 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00016859 | Inferred_automatically | RNAi_primary | ||||
| Expr_pattern | Expr1015287 | |||||
| Expr1154065 | ||||||
| Expr2010691 | ||||||
| Expr2028930 | ||||||
| Drives_construct | WBCnstr00031204 | |||||
| Construct_product | WBCnstr00031204 | |||||
| Microarray_results (18) | ||||||
| Expression_cluster (188) | ||||||
| Interaction | WBInteraction000155640 | |||||
| WBInteraction000156224 | ||||||
| Map_info | Map | X | Position | 11.0455 | ||
| Positive | Positive_clone | K09A11 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
| Pseudo_map_position | ||||||
| Reference | WBPaper00038491 | |||||
| WBPaper00055090 | ||||||
| WBPaper00063971 | ||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
| Method | Gene |
