WormBase Tree Display for Gene: WBGene00010705
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| WBGene00010705 | SMap | S_parent | Sequence | K09A11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyp-14A1 | |||||||
| Sequence_name | K09A11.2 | ||||||||
| Molecular_name | K09A11.2 | ||||||||
| K09A11.2.1 | |||||||||
| CE03473 | |||||||||
| Other_name | CELE_K09A11.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | cyp-14A1 | ||||||||
| DB_info | Database | AceView | gene | XN884 | |||||
| WormQTL | gene | WBGene00010705 | |||||||
| WormFlux | gene | WBGene00010705 | |||||||
| NDB | locus_tag | CELE_K09A11.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00010705|UniProtKB=Q27506 | |||||||
| family | PTHR24284 | ||||||||
| NCBI | gene | 187183 | |||||||
| RefSeq | protein | NM_077802.5 | |||||||
| TrEMBL | UniProtAcc | Q27506 | |||||||
| UniProt_GCRP | UniProtAcc | Q27506 | |||||||
| OMIM | gene | 610670 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-14A1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele | WBVar01499887 | ||||||||
| WBVar01499519 | |||||||||
| WBVar01499888 | |||||||||
| WBVar01499710 | |||||||||
| WBVar01487944 | |||||||||
| WBVar01200269 | |||||||||
| WBVar01200270 | |||||||||
| WBVar01200271 | |||||||||
| WBVar01200272 | |||||||||
| WBVar01200273 | |||||||||
| WBVar01200274 | |||||||||
| WBVar01200275 | |||||||||
| WBVar01200276 | |||||||||
| WBVar01200277 | |||||||||
| WBVar01200278 | |||||||||
| WBVar01200279 | |||||||||
| WBVar01200280 | |||||||||
| WBVar01200281 | |||||||||
| WBVar01200282 | |||||||||
| WBVar01200283 | |||||||||
| WBVar01200284 | |||||||||
| WBVar01200285 | |||||||||
| WBVar01200286 | |||||||||
| WBVar01200287 | |||||||||
| WBVar01200288 | |||||||||
| WBVar01200289 | |||||||||
| WBVar01200290 | |||||||||
| WBVar01200291 | |||||||||
| WBVar01200292 | |||||||||
| WBVar01200293 | |||||||||
| WBVar01759775 | |||||||||
| WBVar00521470 | |||||||||
| WBVar00521471 | |||||||||
| WBVar00521472 | |||||||||
| WBVar00521473 | |||||||||
| WBVar00521474 | |||||||||
| WBVar00521475 | |||||||||
| WBVar00521476 | |||||||||
| WBVar01622058 | |||||||||
| WBVar01572277 | |||||||||
| WBVar01572278 | |||||||||
| WBVar00083983 | |||||||||
| WBVar01954992 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01500067 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00079911 | ||||||||
| 00079912 | |||||||||
| 00079913 | |||||||||
| 00079914 | |||||||||
| 00118047 | |||||||||
| 00118048 | |||||||||
| 00118049 | |||||||||
| 00118050 | |||||||||
| Ortholog (55) | |||||||||
| Paralog (42) | |||||||||
| Structured_description | Concise_description | cyp-14A1 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (12) | ||||||||
| Molecular_info | Corresponding_CDS | K09A11.2 | |||||||
| Corresponding_transcript | K09A11.2.1 | ||||||||
| Other_sequence | EY468469.1 | ||||||||
| PPC09763_1 | |||||||||
| Associated_feature | WBsf982263 | ||||||||
| WBsf238117 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00050360 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00034174 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092632 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116299 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016859 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1015287 | ||||||||
| Expr1154065 | |||||||||
| Expr2010691 | |||||||||
| Expr2028930 | |||||||||
| Drives_construct | WBCnstr00031204 | ||||||||
| Construct_product | WBCnstr00031204 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (188) | |||||||||
| Interaction | WBInteraction000155640 | ||||||||
| WBInteraction000156224 | |||||||||
| Map_info | Map | X | Position | 11.0455 | |||||
| Positive | Positive_clone | K09A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| WBPaper00063971 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
