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WormBase Tree Display for Gene: WBGene00010484

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Name Class

WBGene00010484SMapS_parentSequenceK01H12
IdentityVersion2
NameCGC_namedph-3Person_evidenceWBPerson237
Sequence_nameK01H12.1
Molecular_nameK01H12.1a
K01H12.1a.1
CE03453
K01H12.1b
CE44584
K01H12.1b.1
Other_nameCELE_K01H12.1Accession_evidenceNDBBX284604
Public_namedph-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
218 Aug 2009 11:24:59WBPerson9133Name_changeCGC_namedph-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdph
Allele (12)
StrainWBStrain00026526
RNASeq_FPKM (74)
GO_annotation00007431
00070278
00070279
00070280
00070281
00070282
00070283
00070284
Ortholog (33)
Structured_descriptionConcise_descriptiondph-3 encodes a small protein conserved in diverse eukaryotes, with a CSL motif (a probable zinc finger, sometimes found associated with the N-terminal domain of DnaJ protein); DPH-3 is probably a small subunit or ancillary protein of RNA polymerase II Elongator or of a hypothetical diphthamide synthase complex; DPH-3 is orthologous to mammalian DESR1 (diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1) and S. cerevisiae KTI11; DESR1, and probably KTI11, enables the first step in posttranslational modification of histidine to dipthamide.Paper_evidenceWBPaper00005654
WBPaper00013055
WBPaper00013218
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated18 Aug 2009 00:00:00
Automated_descriptionPredicted to enable ferrous iron binding activity and iron chaperone activity. Predicted to be involved in protein histidyl modification to diphthamide and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Located in nucleus. Is an ortholog of human DPH3 (diphthamide biosynthesis 3) and DPH3P1 (diphthamide biosynthesis 3 pseudogene 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSK01H12.1a
K01H12.1b
Corresponding_transcriptK01H12.1a.1
K01H12.1b.1
Other_sequence (56)
Associated_featureWBsf646248
WBsf228860
Transcription_factorWBTranscriptionFactor000379
Experimental_infoRNAi_resultWBRNAi00025838Inferred_automaticallyRNAi_primary
WBRNAi00027396Inferred_automaticallyRNAi_primary
WBRNAi00016414Inferred_automaticallyRNAi_primary
WBRNAi00025839Inferred_automaticallyRNAi_primary
WBRNAi00092977Inferred_automaticallyRNAi_primary
WBRNAi00115818Inferred_automaticallyRNAi_primary
WBRNAi00049641Inferred_automaticallyRNAi_primary
WBRNAi00033835Inferred_automaticallyRNAi_primary
Expr_patternExpr9502
Expr1019874
Expr1034578
Expr1153368
Expr2011049
Expr2029286
Drives_constructWBCnstr00031386
Construct_productWBCnstr00014067
WBCnstr00031386
Microarray_results (21)
Expression_cluster (121)
InteractionWBInteraction000109978
WBInteraction000109994
WBInteraction000110710
WBInteraction000115367
WBInteraction000120646
WBInteraction000121753
WBInteraction000121865
WBInteraction000177563
WBInteraction000178422
WBInteraction000185744
WBInteraction000192246
WBInteraction000216015
WBInteraction000219723
WBInteraction000219880
WBInteraction000231537
WBInteraction000236664
WBInteraction000245285
WBInteraction000258485
WBInteraction000258616
WBInteraction000275770
WBInteraction000277269
WBInteraction000314442
WBInteraction000317606
WBInteraction000347299
WBInteraction000356974
WBInteraction000357917
WBInteraction000370639
WBInteraction000374054
WBInteraction000381392
WBInteraction000392643
WBInteraction000396485
WBInteraction000397674
WBInteraction000401456
WBInteraction000409163
WBInteraction000415860
WBInteraction000419445
WBInteraction000421050
WBInteraction000422218
WBInteraction000422468
WBInteraction000425657
WBInteraction000432916
WBInteraction000439028
WBInteraction000439192
WBInteraction000443231
WBInteraction000446290
WBInteraction000500297
WBInteraction000500299
WBInteraction000500300
WBInteraction000500301
Map_infoMapIVPosition4.37903Error0.001128
PositivePositive_cloneK01H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027309
WBPaper00036232
WBPaper00038444
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene