WormBase Tree Display for Gene: WBGene00009812

WBGene00009812 SMap: S_parent: Sequence: F47B10
  Identity: Version: 2
    Name: CGC_name: suca-1 Person_evidence: WBPerson1983
            WBPerson261
      Sequence_name: F47B10.1
      Molecular_name: F47B10.1
        F47B10.1.1
        CE03351
      Other_name: CELE_F47B10.1 Accession_evidence: NDB BX284606
      Public_name: suca-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Dec 2011 12:14:43 WBPerson2970 Name_change: CGC_name: suca-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: suca
    Allele (33)
    Strain: WBStrain00051214
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog (36)
    Paralog: WBGene00016844 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable succinate-CoA ligase (ADP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Located in mitochondrion. Expressed in anterior gonad arm. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Is an ortholog of human SUCLA2 (succinate-CoA ligase ADP-forming subunit beta). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080124 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11448)
  Molecular_info: Corresponding_CDS: F47B10.1
    Corresponding_transcript: F47B10.1.1
    Other_sequence (91)
    Associated_feature: WBsf1006844
      WBsf1006845
      WBsf1023778
      WBsf1023779
      WBsf237909
  Experimental_info: RNAi_result: WBRNAi00106979 Inferred_automatically: RNAi_primary
      WBRNAi00015145 Inferred_automatically: RNAi_primary
      WBRNAi00066657 Inferred_automatically: RNAi_primary
      WBRNAi00047594 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr13131
      Expr1013311
      Expr1034287
      Expr1151430
      Expr2017100
      Expr2035236
    Drives_construct: WBCnstr00031900
    Construct_product: WBCnstr00031900
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00032976:non_compensated_genes
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038289:oocyte_protein
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040446:insoluble_protein
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044128:DietaryRestriction_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00046217:gas-1(fc21)_downregulated
      WBPaper00046303:P.aeruginosa_upregulated_protein
      WBPaper00046446:rapid-synthesized_AgingAdult
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050094:glp-1(gf)_upregulated
      WBPaper00050182:lmn-1(L535P)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050599:nicotine(1mM)_upregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00055334:DLC-1_interacting
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056501:P.aeruginosa_downregulated_mitochondria-protein
      WBPaper00056900:PID-3_interacting
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00057162:meg-3_meg-4_downregulated_sRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00059254:CSR-1_interacting
      WBPaper00059440:GLP-1_activated
      WBPaper00059440:LAG-1_activated_48hr-auxin
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:uggt-1_21889-tag-320_20312
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064201:SNA-1_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064257:UNG-1_interacting
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064624:iHg-induced_aggregome
      WBPaper00064716:paraquat_downregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      cgc4489_group_3
      WBPaper00025032:cluster_169
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00028483:Up_mes-4_vs_WT
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00032948:FedUp
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00036286:Pattern_I
      WBPaper00037695:WC_5-day
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040876:mir-35_upregulated
      WBPaper00040963:Q100_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_24h
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecalis_downregulated
      [cgc5767]:cluster_36
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(83_min)
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:Cluster_C
    Interaction (160)
  Map_info: Map: X Position: 2.68095
    Positive: Positive_clone: F47B10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00041022
    WBPaper00049828
    WBPaper00055090
    WBPaper00061547
    WBPaper00065625
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene