WormBase Tree Display for Gene: WBGene00009493
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| WBGene00009493 | SMap | S_parent | Sequence | F36H1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | hrg-4 | Person_evidence | WBPerson1802 | |||||
| Sequence_name | F36H1.5 | ||||||||
| Molecular_name | F36H1.5b | ||||||||
| F36H1.5b.1 | |||||||||
| CE42667 | |||||||||
| F36H1.5c | |||||||||
| CE49968 | |||||||||
| F36H1.5c.1 | |||||||||
| Other_name | CELE_F36H1.5 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | hrg-4 | ||||||||
| DB_info | Database | AceView | gene | 4L794 | |||||
| WormQTL | gene | WBGene00009493 | |||||||
| WormFlux | gene | WBGene00009493 | |||||||
| NDB | locus_tag | CELE_F36H1.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00009493|UniProtKB=Q20106 | |||||||
| family | PTHR31525 | ||||||||
| NCBI | gene | 185380 | |||||||
| RefSeq | protein | NM_001307090.4 | |||||||
| NM_001136385.2 | |||||||||
| SwissProt | UniProtAcc | Q20106 | |||||||
| UniProt_GCRP | UniProtAcc | Q20106 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 18 Apr 2008 13:26:44 | WBPerson2970 | Name_change | CGC_name | hrg-4 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hrg | ||||||||
| Allele (17) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00009495 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00009494 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00019830 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | hrg-4 encodes a transmembrane protein that is conserved amongst nematodes; hrg-4 functions to mediate heme homeostasis, likely by regulating heme transport across the plasma membrane; in vitro, HRG-4 exhibits heme binding over a broad pH range and when expressed in Xenopus oocytes, can stimulate heme-dependent currents; when expressed in HEK293 cells, HRG-4 localizes primarily to the plasma membrane; hrg-4 mRNA expression is significantly upregulated in response to heme deficiency. | Paper_evidence | WBPaper00031703 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 20 Aug 2009 00:00:00 | ||||||||
| Automated_description | Enables heme binding activity and heme transmembrane transporter activity. Involved in heme transport. Located in plasma membrane. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F36H1.5b | |||||||
| F36H1.5c | |||||||||
| Corresponding_CDS_history | F36H1.5a:wp243 | ||||||||
| Corresponding_transcript | F36H1.5b.1 | ||||||||
| F36H1.5c.1 | |||||||||
| Other_sequence | CBC06944_1 | ||||||||
| Associated_feature | WBsf230809 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00031872 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00046518 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014438 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9100 | ||||||||
| Expr9860 | |||||||||
| Expr1012628 | |||||||||
| Expr1150403 | |||||||||
| Expr2012596 | |||||||||
| Expr2030832 | |||||||||
| Drives_construct | WBCnstr00013719 | ||||||||
| WBCnstr00014370 | |||||||||
| WBCnstr00032143 | |||||||||
| Construct_product | WBCnstr00014370 | ||||||||
| WBCnstr00032143 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (228) | |||||||||
| Interaction | WBInteraction000193394 | ||||||||
| WBInteraction000397386 | |||||||||
| WBInteraction000501256 | |||||||||
| WBInteraction000503592 | |||||||||
| WBInteraction000525279 | |||||||||
| WBInteraction000580652 | |||||||||
| Map_info | Map | IV | Position | 4.79269 | Error | 0.001182 | |||
| Positive | Positive_clone | F36H1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
