WormBase Tree Display for Gene: WBGene00009386

WBGene00009386 SMap: S_parent: Sequence: F35B12
  Identity: Version: 2
    Name: CGC_name: tag-290
      Sequence_name: F35B12.6
      Molecular_name: F35B12.6
        F35B12.6.1
        CE05805
      Other_name: CELE_F35B12.6 Accession_evidence: NDB BX284605
      Public_name: tag-290
    DB_info: Database: AceView gene 5M95
        WormQTL gene WBGene00009386
        WormFlux gene WBGene00009386
        NDB locus_tag CELE_F35B12.6
        Panther gene CAEEL|WormBase=WBGene00009386|UniProtKB=Q20014
          family PTHR46339
        NCBI gene 179593
        RefSeq protein NM_073544.5
        TREEFAM TREEFAM_ID TF327278
        TrEMBL UniProtAcc Q20014
        UniProt_GCRP UniProtAcc Q20014
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 22 Apr 2005 11:55:18 WBPerson2970 Name_change: CGC_name: tag-290
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tag
    Allele (26)
    Strain: WBStrain00003451
      WBStrain00036196
    RNASeq_FPKM (74)
    GO_annotation: 00117091
    Ortholog (32)
    Paralog (27)
    Structured_description: Automated_description: Predicted to enable serine-type endopeptidase inhibitor activity. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); leukemia (multiple); and thrombophilia (multiple). Is an ortholog of human TFPI (tissue factor pathway inhibitor) and TFPI2 (tissue factor pathway inhibitor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (25)
  Molecular_info (4)
  Experimental_info: RNAi_result: WBRNAi00033630 Inferred_automatically: RNAi_primary
      WBRNAi00046275 Inferred_automatically: RNAi_primary
      WBRNAi00089069 Inferred_automatically: RNAi_primary
      WBRNAi00014286 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram347
      Expr5949
      Expr1028743
      Expr1150166
      Expr2017262
      Expr2035398
    Drives_construct: WBCnstr00003914
      WBCnstr00032230
    Construct_product: WBCnstr00032230
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00042561:smgl-2(RNAi)_upregulated
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045774:clk-1_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048690:gonad-hermaphrodite-biased
      WBPaper00048988:neuron_expressed
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055648:anterior-head_expressed
      WBPaper00055648:pharynx_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056290:mdt-15(mg584)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058927:high-redox-state_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059378:cec-4(ok3124);lmn-1(Y59C)_vs_lmn-1(Y59C)_downregulated
      WBPaper00059378:lmn-1(Y59C)_upregulated
      WBPaper00059605:simr-1(cmp36)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061340:ant_arc_V
      WBPaper00061340:hyp1V_and_ant_arc_V
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061527:K04C2.5-ZK1307.2
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_downregulated_protein
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065158:AFD_depleted
      WBPaper00065623:93
      WBPaper00065623:118
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:21_0
      WBPaper00065841:21_1
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00030985:Erwinia_carotovora_downregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00032062:age_regulated_genes
      WBPaper00032948:FedUp
      WBPaper00036286:Pattern_I
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00051387:Triclosan_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
    Interaction: WBInteraction000123194
      WBInteraction000288409
      WBInteraction000389883
      WBInteraction000442665
      WBInteraction000547983
  Map_info: Map: V Position: 3.21769 Error: 0.002354
    Positive: Positive_clone: F35B12 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5169
        4169
        5449
        5515
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00059378
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene