WormBase Tree Display for Gene: WBGene00009304
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WBGene00009304 | SMap | S_parent | Sequence | F32A7 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | eva | ||||||
Allele (99) | |||||||
Strain | WBStrain00036134 | ||||||
WBStrain00054912 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00002163 | ||||||
00101597 | |||||||
00101598 | |||||||
00101599 | |||||||
00101600 | |||||||
00101601 | |||||||
00101602 | |||||||
00117029 | |||||||
Ortholog (33) | |||||||
Paralog | WBGene00002251 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00002252 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00007664 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00014035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00015735 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00017947 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00017948 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | eva-1 encodes, by alternative splicing, two isoforms of a cell-surface protein that acts cell-autonomously with SAX-3 as a SLT-1 receptor subunit, and is required for guidance of the AVM pioneer axon to the ventral nerve cord; EVA-1's long isoform is predicted to have a signal sequence, an ectodomain with two lectinlike galactose-binding sequences, a single transmembrane sequence, and a cytodomain with a phosphotyrosine binding motif; homologs of EVA-1 include human C21orf63; EVA-1 is expressed in embryonic neurons during axonal growth, head and tail neurons, the ventral nerve cord, pharyngeal and body wall muscles, hypodermis, uterus and vulva; ectopic EVA-1 expression in touch-receptor neurons causes the cell body of ALM to be displaced anteriorly (due to failed posterior migration) in a SLT-1-dependent manner; the cytodomain of EVA-1 is functionally dispensable in vivo; eva-1 mutants enhance the ventral-axon guidance defects of unc-40 mutants; EVA-1, SLT-1, and SAX-3 bind one another in vitro. | Paper_evidence | WBPaper00031043 | |||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 29 Dec 2007 00:00:00 | ||||||
Automated_description | Predicted to enable carbohydrate binding activity. Located in M band; cell junction; and striated muscle dense body. Expressed in body wall musculature; hypodermis; pharyngeal muscle cell; and ventral nerve cord. Is an ortholog of human EVA1C (eva-1 homolog C). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F32A7.3a | |||||
F32A7.3b | |||||||
F32A7.3c | |||||||
Corresponding_CDS_history | F32A7.3a:wp114 | ||||||
F32A7.3b:wp114 | |||||||
Corresponding_transcript | F32A7.3a.1 | ||||||
F32A7.3b.1 | |||||||
F32A7.3b.2 | |||||||
F32A7.3b.3 | |||||||
F32A7.3b.4 | |||||||
F32A7.3c.1 | |||||||
Other_sequence | Oden_isotig19651 | ||||||
FD514519.1 | |||||||
CJC06290_1 | |||||||
CRC10951_1 | |||||||
CBC04911_1 | |||||||
CSC00310_1 | |||||||
Associated_feature (13) | |||||||
Experimental_info | RNAi_result | WBRNAi00109732 | Inferred_automatically | RNAi_primary | |||
WBRNAi00066624 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00046088 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00109779 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00109638 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00101830 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00031650 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116608 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00003551 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00109685 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr4895 | ||||||
Expr9367 | |||||||
Expr1015991 | |||||||
Expr1034065 | |||||||
Expr1149975 | |||||||
Expr2011386 | |||||||
Expr2029622 | |||||||
Drives_construct | WBCnstr00012316 | ||||||
WBCnstr00019877 | |||||||
WBCnstr00032298 | |||||||
Construct_product | WBCnstr00012316 | ||||||
WBCnstr00013932 | |||||||
WBCnstr00019586 | |||||||
WBCnstr00019593 | |||||||
WBCnstr00019594 | |||||||
WBCnstr00032298 | |||||||
Antibody | WBAntibody00001309 | ||||||
Microarray_results (30) | |||||||
Expression_cluster (229) | |||||||
Interaction | WBInteraction000028967 | ||||||
WBInteraction000262189 | |||||||
WBInteraction000524192 | |||||||
WBInteraction000543558 | |||||||
WBInteraction000551356 | |||||||
WBInteraction000551357 | |||||||
WBInteraction000551359 | |||||||
WBInteraction000555696 | |||||||
WBInteraction000555697 | |||||||
WBInteraction000555698 | |||||||
Map_info | Map | I | Position | 27.9483 | Error | 0.004097 | |
Positive | Positive_clone | F32A7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 5192 | |||||
Pseudo_map_position | |||||||
Reference (15) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |