WormBase Tree Display for Gene: WBGene00009304
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| WBGene00009304 | SMap | S_parent | Sequence | F32A7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | eva-1 | Paper_evidence | WBPaper00031043 | |||||
| Person_evidence | WBPerson2189 | ||||||||
| WBPerson893 | |||||||||
| Sequence_name | F32A7.3 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | tag-271 | ||||||||
| CELE_F32A7.3 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | eva-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 22 Apr 2005 11:55:18 | WBPerson2970 | Name_change | CGC_name | tag-271 | ||||
| 3 | 09 Oct 2007 15:40:26 | WBPerson2970 | Name_change | CGC_name | eva-1 | ||||
| Other_name | tag-271 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | eva | ||||||||
| Allele (99) | |||||||||
| Strain | WBStrain00036134 | ||||||||
| WBStrain00054912 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00002163 | ||||||||
| 00101597 | |||||||||
| 00101598 | |||||||||
| 00101599 | |||||||||
| 00101600 | |||||||||
| 00101601 | |||||||||
| 00101602 | |||||||||
| 00117029 | |||||||||
| Ortholog (33) | |||||||||
| Paralog | WBGene00002251 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00002252 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00007664 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00014035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00015735 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00017947 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00017948 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | eva-1 encodes, by alternative splicing, two isoforms of a cell-surface protein that acts cell-autonomously with SAX-3 as a SLT-1 receptor subunit, and is required for guidance of the AVM pioneer axon to the ventral nerve cord; EVA-1's long isoform is predicted to have a signal sequence, an ectodomain with two lectinlike galactose-binding sequences, a single transmembrane sequence, and a cytodomain with a phosphotyrosine binding motif; homologs of EVA-1 include human C21orf63; EVA-1 is expressed in embryonic neurons during axonal growth, head and tail neurons, the ventral nerve cord, pharyngeal and body wall muscles, hypodermis, uterus and vulva; ectopic EVA-1 expression in touch-receptor neurons causes the cell body of ALM to be displaced anteriorly (due to failed posterior migration) in a SLT-1-dependent manner; the cytodomain of EVA-1 is functionally dispensable in vivo; eva-1 mutants enhance the ventral-axon guidance defects of unc-40 mutants; EVA-1, SLT-1, and SAX-3 bind one another in vitro. | Paper_evidence | WBPaper00031043 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 29 Dec 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable carbohydrate binding activity. Located in M band; cell junction; and striated muscle dense body. Expressed in body wall musculature; hypodermis; pharyngeal muscle cell; and ventral nerve cord. Is an ortholog of human EVA1C (eva-1 homolog C). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F32A7.3a | |||||||
| F32A7.3b | |||||||||
| F32A7.3c | |||||||||
| Corresponding_CDS_history | F32A7.3a:wp114 | ||||||||
| F32A7.3b:wp114 | |||||||||
| Corresponding_transcript | F32A7.3a.1 | ||||||||
| F32A7.3b.1 | |||||||||
| F32A7.3b.2 | |||||||||
| F32A7.3b.3 | |||||||||
| F32A7.3b.4 | |||||||||
| F32A7.3c.1 | |||||||||
| Other_sequence | Oden_isotig19651 | ||||||||
| FD514519.1 | |||||||||
| CJC06290_1 | |||||||||
| CRC10951_1 | |||||||||
| CBC04911_1 | |||||||||
| CSC00310_1 | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00109732 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00066624 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046088 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109779 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109638 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101830 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031650 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116608 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003551 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109685 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4895 | ||||||||
| Expr9367 | |||||||||
| Expr1015991 | |||||||||
| Expr1034065 | |||||||||
| Expr1149975 | |||||||||
| Expr2011386 | |||||||||
| Expr2029622 | |||||||||
| Drives_construct | WBCnstr00012316 | ||||||||
| WBCnstr00019877 | |||||||||
| WBCnstr00032298 | |||||||||
| Construct_product (6) | |||||||||
| Antibody | WBAntibody00001309 | ||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (229) | |||||||||
| Interaction | WBInteraction000028967 | ||||||||
| WBInteraction000262189 | |||||||||
| WBInteraction000524192 | |||||||||
| WBInteraction000543558 | |||||||||
| WBInteraction000551356 | |||||||||
| WBInteraction000551357 | |||||||||
| WBInteraction000551359 | |||||||||
| WBInteraction000555696 | |||||||||
| WBInteraction000555697 | |||||||||
| WBInteraction000555698 | |||||||||
| Map_info | Map | I | Position | 27.9483 | Error | 0.004097 | |||
| Positive | Positive_clone | F32A7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5192 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031043 | ||||||||
| WBPaper00032413 | |||||||||
| WBPaper00038444 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00038663 | |||||||||
| WBPaper00040235 | |||||||||
| WBPaper00045615 | |||||||||
| WBPaper00049528 | |||||||||
| WBPaper00053600 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00057546 | |||||||||
| WBPaper00058323 | |||||||||
| WBPaper00063669 | |||||||||
| WBPaper00064099 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
