WormBase Tree Display for Gene: WBGene00009127
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| WBGene00009127 | SMap | S_parent | Sequence | F25H5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | clsp-1 | Person_evidence | WBPerson4143 | |||||
| Sequence_name | F25H5.5 | ||||||||
| Molecular_name | F25H5.5a | ||||||||
| F25H5.5a.1 | |||||||||
| CE42710 | |||||||||
| F25H5.5b | |||||||||
| CE46262 | |||||||||
| F25H5.5b.1 | |||||||||
| Other_name | CELE_F25H5.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | clsp-1 | ||||||||
| DB_info | Database | AceView | gene | 1J736 | |||||
| WormQTL | gene | WBGene00009127 | |||||||
| WormFlux | gene | WBGene00009127 | |||||||
| NDB | locus_tag | CELE_F25H5.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00009127|UniProtKB=O17838 | |||||||
| family | PTHR14396 | ||||||||
| NCBI | gene | 172742 | |||||||
| RefSeq | protein | NM_001377615.2 | |||||||
| NM_001264079.3 | |||||||||
| TREEFAM | TREEFAM_ID | TF321962 | |||||||
| TrEMBL | UniProtAcc | G3MU54 | |||||||
| O17838 | |||||||||
| UniProt_GCRP | UniProtAcc | O17838 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 07 Jun 2016 16:25:01 | WBPerson2970 | Name_change | CGC_name | clsp-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | clsp | ||||||||
| Allele (50) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00009076 | ||||||||
| 00009077 | |||||||||
| 00009078 | |||||||||
| 00009079 | |||||||||
| 00009080 | |||||||||
| 00009081 | |||||||||
| Contained_in_operon | CEOP1540 | ||||||||
| Ortholog (27) | |||||||||
| Structured_description | Concise_description | F25H5.5 encodes the C. elegans homologue of Claspin, an S-phase checkpoint component that interacts with Chk1 and negatively regulates cell cycle progression; in wild-type animals, loss of F25H5.5 activity results in some embryonic lethality; loss of F25H5.5 activity in a lin-35 mutant background, however, results in sterility, as well as smaller than normal body size, uncoordinated locomotion, and a protruding vulva; weaker F25H5.5 RNAi phenotypes are seen in lin-15B and eri-1; lin-15B backgrounds. | Paper_evidence | WBPaper00004651 | |||||
| WBPaper00029258 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 14 Feb 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable anaphase-promoting complex binding activity. Predicted to be involved in mitotic DNA replication checkpoint signaling and mitotic G2 DNA damage checkpoint signaling. Located in nucleus. Is an ortholog of human CLSPN (claspin). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F25H5.5a | |||||||
| F25H5.5b | |||||||||
| Corresponding_CDS_history | F25H5.5:wp192 | ||||||||
| Corresponding_transcript | F25H5.5a.1 | ||||||||
| F25H5.5b.1 | |||||||||
| Other_sequence (33) | |||||||||
| Associated_feature | WBsf649452 | ||||||||
| WBsf220047 | |||||||||
| WBsf220048 | |||||||||
| WBsf220049 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr8725 | ||||||||
| Expr1026132 | |||||||||
| Expr1033977 | |||||||||
| Expr1149465 | |||||||||
| Expr2010255 | |||||||||
| Expr2028497 | |||||||||
| Drives_construct | WBCnstr00032443 | ||||||||
| Construct_product | WBCnstr00007587 | ||||||||
| WBCnstr00013483 | |||||||||
| WBCnstr00032443 | |||||||||
| Antibody | WBAntibody00002990 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (120) | |||||||||
| Interaction (39) | |||||||||
| Map_info | Map | I | Position | 3.63002 | |||||
| Positive | Positive_clone | F25H5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00029258 | ||||||||
| WBPaper00033469 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049963 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062444 | |||||||||
| WBPaper00066002 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
