WormBase Tree Display for Gene: WBGene00009004
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| WBGene00009004 | SMap | S_parent | Sequence | F21C3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pfd-6 | Person_evidence | WBPerson3663 | |||||
| WBPerson2136 | |||||||||
| Sequence_name | F21C3.5 | ||||||||
| Molecular_name | F21C3.5 | ||||||||
| F21C3.5.1 | |||||||||
| CE05680 | |||||||||
| Other_name | CELE_F21C3.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | pfd-6 | ||||||||
| DB_info | Database | AceView | gene | 1H860 | |||||
| WormQTL | gene | WBGene00009004 | |||||||
| WormFlux | gene | WBGene00009004 | |||||||
| NDB | locus_tag | CELE_F21C3.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00009004|UniProtKB=P52554 | |||||||
| family | PTHR21431 | ||||||||
| NCBI | gene | 172474 | |||||||
| RefSeq | protein | NM_059657.6 | |||||||
| SwissProt | UniProtAcc | P52554 | |||||||
| TREEFAM | TREEFAM_ID | TF315166 | |||||||
| UniProt_GCRP | UniProtAcc | P52554 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Aug 2006 11:39:27 | WBPerson2970 | Name_change | CGC_name | pfd-6 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pfd | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00027642 | ||||||||
| WBStrain00037185 | |||||||||
| WBStrain00037512 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP1384 | ||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | pfd-6 encodes a putative prefoldin 6 subunit, orthologous to human PFDN6 (OMIM:605660), required for normal microtubule growth and distal tip cell migration; PFD-6 is expressed cytoplasmically in most, if not all, tissues, including the germline; in mass RNAi assays, PFD-6 is required for normal mitotic spindle position, embryonic and larval viability, fertility, body shape, vulval development, and locomotion, and for normally rapid growth; pfd-6(RNAi) embryos show a reduced microtubule growth rate. | Paper_evidence | WBPaper00004402 | |||||
| WBPaper00006395 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00028783 | |||||||||
| WBPaper00031309 | |||||||||
| WBPaper00031362 | |||||||||
| WBPaper00031363 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 14 Jan 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in cytoplasm. Expressed in body wall musculature; hypodermal cell; intestinal cell; and non-striated muscle. Is an ortholog of human PFDN6 (prefoldin subunit 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F21C3.5 | |||||||
| Corresponding_transcript | F21C3.5.1 | ||||||||
| Other_sequence (31) | |||||||||
| Associated_feature | WBsf649304 | ||||||||
| WBsf664429 | |||||||||
| WBsf219731 | |||||||||
| WBsf219732 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr7841 | ||||||||
| Expr14586 | |||||||||
| Expr1020376 | |||||||||
| Expr1033920 | |||||||||
| Expr1149123 | |||||||||
| Expr2014846 | |||||||||
| Expr2033081 | |||||||||
| Drives_construct | WBCnstr00001361 | ||||||||
| WBCnstr00032533 | |||||||||
| WBCnstr00041173 | |||||||||
| Construct_product | WBCnstr00032533 | ||||||||
| WBCnstr00041173 | |||||||||
| Regulate_expr_cluster | WBPaper00055827:pfd-6(gk493446)_downregulated | ||||||||
| WBPaper00055827:pfd-6(gk493446)_upregulated | |||||||||
| Antibody | WBAntibody00001342 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (133) | |||||||||
| Interaction (152) | |||||||||
| Map_info | Map | I | Position | 1.87364 | Error | 0.000337 | |||
| Positive | Positive_clone | F21C3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031309 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00051688 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00055827 | |||||||||
| WBPaper00057394 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
