WormBase Tree Display for Gene: WBGene00008956

WBGene00008956 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 3
    Name: CGC_name: nekl-3 Person_evidence: WBPerson353
      Sequence_name: F19H6.1
      Molecular_name: F19H6.1
        F19H6.1.1
        CE31484
        F19H6.1.2
      Other_name: mlt-1 Person_evidence: WBPerson709
            WBPerson664
        CELE_F19H6.1 Accession_evidence: NDB BX284606
      Public_name: nekl-3
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 16 Feb 2007 14:39:36 WBPerson2970 Name_change: CGC_name: nekl-3
        3 03 May 2007 10:33:07 WBPerson2970 Name_change: Other_name: mlt-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nekl
    Allele (37)
    Strain: WBStrain00003141
      WBStrain00036371
    Component_of_genotype: WBGenotype00000047
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (43)
    Paralog: WBGene00013694 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00017033 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020324 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021461 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00022631 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable protein serine/threonine kinase activity. Involved in gonad development and molting cycle. Located in apical plasma membrane. Expressed in hyp7 syncytium; hypodermal cell; neurons; and vulva. Is an ortholog of human NEK7 (NIMA related kinase 7). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Modifies_disease: DOID:12377
  Modifies_disease_in_annotation: WBDOannot00000884
  Molecular_info: Corresponding_CDS: F19H6.1
    Corresponding_CDS_history: F19H6.1:wp83
    Corresponding_transcript: F19H6.1.1
      F19H6.1.2
    Other_sequence (28)
    Associated_feature: WBsf718724
      WBsf238061
  Experimental_info: RNAi_result: WBRNAi00031140 Inferred_automatically: RNAi_primary
      WBRNAi00027289 Inferred_automatically: RNAi_primary
      WBRNAi00013573 Inferred_automatically: RNAi_primary
      WBRNAi00025146 Inferred_automatically: RNAi_primary
      WBRNAi00045041 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1134
      Chronogram1590
      Expr5796
      Expr12110
      Expr15101
      Expr1010616
      Expr1149003
      Expr2013954
      Expr2032193
    Drives_construct: WBCnstr00003278
      WBCnstr00004569
      WBCnstr00019130
      WBCnstr00032568
    Construct_product: WBCnstr00020082
      WBCnstr00032568
    Microarray_results (18)
    Expression_cluster: WBPaper00029359_1166
      WBPaper00029359_1197
      WBPaper00029359_1291
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_rde-4
      WBPaper00032425:down_in_zfp-1
      WBPaper00032976:dosage_compensated_genes
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:dopaminergic-neurons_CoreEnriched
      WBPaper00037950:dopaminergic-neurons_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_embryo_SelectivelyEnriched
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_CoreEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046509:htz-1(ok3099)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061340:ALM_PLM
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:tnt-4-myo-1_2160
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064716:paraquat_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_6
      WBPaper00035873:dpy-9_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_I
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      [cgc6390]:Cluster_B
    Interaction (57)
  Map_info: Map: X Position: 7.03746 Error: 0.001276
    Positive: Positive_clone: F19H6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (25)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene