Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00008829

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00008829SMapS_parentSequenceF14H3
IdentityVersion2
NameCGC_namecyp-35D1
Sequence_nameF14H3.10
Molecular_nameF14H3.10
F14H3.10.1
CE15834
Other_nameCELE_F14H3.10Accession_evidenceNDBBX284605
Public_namecyp-35D1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 Sep 2004 09:38:16WBPerson1971Name_changeCGC_namecyp-35D1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyp
Allele (140)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (56)
Paralog (45)
Structured_descriptionAutomated_descriptionPredicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2E1 (cytochrome P450 family 2 subfamily E member 1); and CYP2S1 (cytochrome P450 family 2 subfamily S member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (30)
Molecular_infoCorresponding_CDSF14H3.10
Corresponding_transcriptF14H3.10.1
Associated_feature (5)
Experimental_infoRNAi_resultWBRNAi00092690Inferred_automaticallyRNAi_primary
WBRNAi00044650Inferred_automaticallyRNAi_primary
WBRNAi00114407Inferred_automaticallyRNAi_primary
WBRNAi00030966Inferred_automaticallyRNAi_primary
WBRNAi00114406Inferred_automaticallyRNAi_primary
WBRNAi00013318Inferred_automaticallyRNAi_primary
Expr_patternExpr1010619
Expr1148623
Expr2010741
Expr2028977
Drives_constructWBCnstr00018363
WBCnstr00032652
Construct_productWBCnstr00032652
Microarray_results (16)
Expression_clusterWBPaper00004966:beta-Naphthoflavone_induced
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00042194:Tryptophan_upregulated
WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
WBPaper00042561:smg-2(RNAi)_downregulated
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044030:nhr-8(hd117)_downregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045774:clk-1_downregulated
WBPaper00046121:endoderm_unique
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046527:glucose_downregulated
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00048923:Aging_regulated
WBPaper00049334:CE_intestine_enriched
WBPaper00049368:daf-2(e1370)_downregulated
WBPaper00049377:MWCNT_upregulated
WBPaper00049498:npr-1(ur89)_regulated_7
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049736:15deg-then-25deg(12hr)_downregulated_N2
WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
WBPaper00049920:Glucose-Diet_downregulated_N2
WBPaper00050561:indole_0.1mM-indole_upregulated
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00051021:4-bromodiphenyl-ether_upregulated
WBPaper00051039:intestine_enriched
WBPaper00051257:Levamisole_upregulated
WBPaper00051265:F1_hrde-1(tm1200)_upregulated
WBPaper00051404:alg-1(gk214)_downregulated
WBPaper00051558:aging_regulated
WBPaper00053388:dauer_regulated_Cluster6
WBPaper00053402:cco-1(RNAi)_downregulated
WBPaper00053402:his-3(RNAi)_downregulated
WBPaper00053664:ins-11(tm1053)_upregulated
WBPaper00053771:up_at_3h-NaCl
WBPaper00053771:up_at_24h-NaCl
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00054872:egl-9(sa307)_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00056039:ptl-1(ok621)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056169:rrf-3(pk1426)_downregulated_embryo
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056284:ints-1(RNAi)_upregulated
WBPaper00056290:mdt-15(mg584)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:flcn-1(ok975)_downregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00057068:ints-4(RNAi)_downregulated
WBPaper00057143:ztf-11(RNAi)_downregulated
WBPaper00058598:mex-1(or286)_downregulated
WBPaper00058598:mex-3(eu149)_downregulated
WBPaper00058598:spn-4(tm291)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00058711:paraquat_upregulated
WBPaper00058711:skn-1(lax188)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00058969:RIS_depleted
WBPaper00059117:B.subtilis_downregulated
WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
WBPaper00059604:fluvastatin_downregulated_N2
WBPaper00059739:hira-1(gk835598)_downregulated_L4
WBPaper00059987:Wounding_upregulated
WBPaper00060273:isp-1(qm150)_downregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_depleted
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061340:Intestine
WBPaper00061341:28C_48h_downregulated
WBPaper00061527:gst-26-pho-1_10767
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00061853:osm-3(dh441)_downregulated
WBPaper00061853:tunicamycin_upregulated_N2
WBPaper00062078:NMR-HspB1_regulated
WBPaper00062118:neural-HSF-1_downregulated
WBPaper00062146:MOG-7-degron_1h_regulated
WBPaper00062305:P.brevicompactum_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062669:extracellular-vesicle_protein
WBPaper00062672:dcp-66(RNAi)_upregulated
WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064382:auxin_upregulated
WBPaper00064532:pals-22(jy3)_downregulated
WBPaper00064632:daf-2(e1370)_upregulated_intestine
WBPaper00064716:paraquat_downregulated
WBPaper00064871:PA14_upregulated_AWA
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065158:25C_vs_15C_downregulated_AFD
WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
WBPaper00065272:dhgd-1(tm6671)_downregulated
WBPaper00065288:mdt-15(tm2182)_downregulated
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065984:pals-17(syb3980)_downregulated
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:Doxorubicin_downregulated_diploid
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
WBPaper00025032:cluster_5
WBPaper00028789:PA14_vs_OP50_upregulated_8hr
WBPaper00030985:Photorhabdus_luminescens_upregulated
WBPaper00032948:FedUp
WBPaper00036130:mir-243_down_regulated
WBPaper00036286:Pattern_D
WBPaper00037695:WC_5-day
WBPaper00038172:tax-6null_down_regulated
WBPaper00038462:aging_downregulated
WBPaper00039792:TempShiftIncrease
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_developing
WBPaper00040858:eQTL_regulated_juvenile
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00041211:RPW-24_Up
WBPaper00041267:SpaceFlight_Downregulated
WBPaper00042274:tbx-2(bx59)_downregulated
WBPaper00046083:oga-1(ok1207)_OP50_upregulated
WBPaper00046083:ogt-1(ok1474)_OP50_upregulated
WBPaper00046548:dafachronic-acid_upregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00047070:xpa-1_UV_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00055899:2,4-Dinitroanisole_regulated
WBPaper00055899:nitroguanidine_regulated
WBPaper00056330:mrps-5(RNAi)_downregulated
Interaction (18)
Map_infoMapVPosition9.44886Error0.003556
PositivePositive_cloneF14H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00043063
WBPaper00044018
WBPaper00062515
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene