WormBase Tree Display for Gene: WBGene00008764
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| WBGene00008764 | SMap | S_parent | Sequence | F13G3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dylt-1 | Person_evidence | WBPerson3088 | |||||
| Sequence_name | F13G3.4 | ||||||||
| Molecular_name | F13G3.4 | ||||||||
| F13G3.4.1 | |||||||||
| CE17659 | |||||||||
| Other_name | CELE_F13G3.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | dylt-1 | ||||||||
| DB_info | Database | AceView | gene | 1H876 | |||||
| WormQTL | gene | WBGene00008764 | |||||||
| WormFlux | gene | WBGene00008764 | |||||||
| NDB | locus_tag | CELE_F13G3.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00008764|UniProtKB=Q19416 | |||||||
| family | PTHR21255 | ||||||||
| NCBI | gene | 172476 | |||||||
| RefSeq | protein | NM_059662.7 | |||||||
| TrEMBL | UniProtAcc | Q19416 | |||||||
| UniProt_GCRP | UniProtAcc | Q19416 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 01 Apr 2005 11:05:24 | WBPerson2970 | Name_change | CGC_name | dylt-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dylt | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00031403 | ||||||||
| WBStrain00031404 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00064654 | ||||||||
| 00064655 | |||||||||
| 00064656 | |||||||||
| 00064657 | |||||||||
| Contained_in_operon | CEOP1388 | ||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00017014 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00011469 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | dylt-1 encodes a putative dynein light chain subunit that inhibits DHC-1 in vivo, but is otherwise dispensable for viability; DYLT-1 is paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); dylt-1(RNAi) and dylt-1(ok417) both suppress the lethality of conditional dhc-1 mutations, and dylt-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYLT-1 negatively regulates dynein; in oocytes and early embryos, DYLT-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYLT-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature. | Paper_evidence | WBPaper00029395 | |||||
| WBPaper00030897 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 26 Aug 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytoplasm. Predicted to be part of cytoplasmic dynein complex. Expressed in ADFL and ADFR. Is an ortholog of human DYNLT1 (dynein light chain Tctex-type 1) and DYNLT3 (dynein light chain Tctex-type 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F13G3.4 | |||||||
| Corresponding_transcript | F13G3.4.1 | ||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf219735 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00091213 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00044538 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003371 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091212 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111643 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082363 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116917 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030905 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090797 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4799 | ||||||||
| Expr9585 | |||||||||
| Expr1021629 | |||||||||
| Expr1033822 | |||||||||
| Expr1148492 | |||||||||
| Expr2011139 | |||||||||
| Expr2029375 | |||||||||
| Drives_construct | WBCnstr00014149 | ||||||||
| WBCnstr00032707 | |||||||||
| Construct_product | WBCnstr00001415 | ||||||||
| WBCnstr00017937 | |||||||||
| WBCnstr00032707 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (106) | |||||||||
| Interaction (63) | |||||||||
| Map_info | Map | I | Position | 1.87613 | Error | 0.001737 | |||
| Positive | Positive_clone | F13G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5159 | |||||||
| 5331 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027822 | ||||||||
| WBPaper00029395 | |||||||||
| WBPaper00030897 | |||||||||
| WBPaper00035010 | |||||||||
| WBPaper00035192 | |||||||||
| WBPaper00037839 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039784 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00057728 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
