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WormBase Tree Display for Gene: WBGene00008764

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WBGene00008764	SMap	S_parent	Sequence	F13G3
	Identity	Version	2
		Name	CGC_name	dylt-1	Person_evidence	WBPerson3088
			Sequence_name	F13G3.4
			Molecular_name	F13G3.4
				F13G3.4.1
				CE17659
			Other_name	CELE_F13G3.4	Accession_evidence	NDB	BX284601
			Public_name	dylt-1
		DB_info	Database	AceView	gene	1H876
				WormQTL	gene	WBGene00008764
				WormFlux	gene	WBGene00008764
				NDB	locus_tag	CELE_F13G3.4
				Panther	gene	CAEEL\|WormBase=WBGene00008764\|UniProtKB=Q19416
					family	PTHR21255
				NCBI	gene	172476
				RefSeq	protein	NM_059662.7
				TrEMBL	UniProtAcc	Q19416
				UniProt_GCRP	UniProtAcc	Q19416
		Species	Caenorhabditis elegans
		History	Version_change	1	26 May 2004 16:54:49	WBPerson1971	Event	Imported	Initial conversion from CDS class of WS125
				2	01 Apr 2005 11:05:24	WBPerson2970	Name_change	CGC_name	dylt-1
		Status	Live
	Gene_info	Biotype	SO:0001217
		Gene_class	dylt
		Allele (15)
		Strain	WBStrain00031403
			WBStrain00031404
		RNASeq_FPKM (74)
		GO_annotation	00064654
			00064655
			00064656
			00064657
		Contained_in_operon	CEOP1388
		Ortholog	WBGene00072267	Caenorhabditis remanei	From_analysis	OMA
						Inparanoid_8
						WormBase-Compara
			WBGene00040567	Caenorhabditis briggsae	From_analysis	Hillier-set
						OrthoMCL
						OMA
						Inparanoid_8
						WormBase-Compara
			WBGene00101609	Pristionchus pacificus	From_analysis	OMA
						Inparanoid_8
			WBGene00149858	Caenorhabditis brenneri	From_analysis	OMA
						Inparanoid_8
			WBGene00125367	Caenorhabditis japonica	From_analysis	OMA
						Inparanoid_8
						WormBase-Compara
			CBOVI.g9025	Caenorhabditis bovis	From_analysis	WormBase-Compara
			CSP21.g4398	Caenorhabditis parvicauda	From_analysis	WormBase-Compara
			CSP31.g53	Caenorhabditis uteleia	From_analysis	WormBase-Compara
			CSP32.g935	Caenorhabditis sulstoni	From_analysis	WormBase-Compara
			CSP39.g7263	Caenorhabditis waitukubuli	From_analysis	WormBase-Compara
			Cni-dylt-1	Caenorhabditis nigoni	From_analysis	WormBase-Compara
			Csp11.Scaffold630.g17283	Caenorhabditis tropicalis	From_analysis	WormBase-Compara
			FL83_24364	Caenorhabditis latens	From_analysis	WormBase-Compara
			GCK72_000152	Caenorhabditis remanei	From_analysis	WormBase-Compara
			OTIPU.nOt.2.0.1.g05638	Oscheius tipulae	From_analysis	WormBase-Compara
			OTIPU.nOt.2.0.1.g12119	Oscheius tipulae	From_analysis	WormBase-Compara
			Sp34_10090500	Caenorhabditis inopinata	From_analysis	WormBase-Compara
			chrI_pilon.g1359	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00218962	Caenorhabditis japonica	From_analysis	WormBase-Compara
			FB:FBgn0024432	Drosophila melanogaster	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-040927-24	Danio rerio	From_analysis	Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-041210-9	Danio rerio	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			ZFIN:ZDB-GENE-060503-292	Danio rerio	From_analysis	Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:11694	Homo sapiens	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			HGNC:11697	Homo sapiens	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:98643	Mus musculus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:1914367	Mus musculus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:3780996	Mus musculus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:3807476	Mus musculus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			MGI:3807506	Mus musculus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:620261	Rattus norvegicus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
			RGD:1549755	Rattus norvegicus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						SonicParanoid
		Paralog	WBGene00017014	Caenorhabditis elegans	From_analysis	Panther
			WBGene00011469	Caenorhabditis elegans	From_analysis	Panther
		Structured_description	Concise_description	dylt-1 encodes a putative dynein light chain subunit that inhibits DHC-1 in vivo, but is otherwise dispensable for viability; DYLT-1 is paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); dylt-1(RNAi) and dylt-1(ok417) both suppress the lethality of conditional dhc-1 mutations, and dylt-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYLT-1 negatively regulates dynein; in oocytes and early embryos, DYLT-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYLT-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.	Paper_evidence	WBPaper00029395
						WBPaper00030897
					Curator_confirmed	WBPerson567
					Date_last_updated	26 Aug 2007 00:00:00
			Automated_description	Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytoplasm. Predicted to be part of cytoplasmic dynein complex. Expressed in ADFL and ADFR. Is an ortholog of human DYNLT1 (dynein light chain Tctex-type 1) and DYNLT3 (dynein light chain Tctex-type 3).	Paper_evidence	WBPaper00065943
					Curator_confirmed	WBPerson324
						WBPerson37462
					Inferred_automatically	This description was generated automatically by a script based on data from the WS291 version of WormBase
					Date_last_updated	29 Nov 2023 00:00:00
	Molecular_info	Corresponding_CDS	F13G3.4
		Corresponding_transcript	F13G3.4.1
		Other_sequence (18)
		Associated_feature	WBsf219735
	Experimental_info	RNAi_result	WBRNAi00091213	Inferred_automatically	RNAi_primary
			WBRNAi00044538	Inferred_automatically	RNAi_primary
			WBRNAi00003371	Inferred_automatically	RNAi_primary
			WBRNAi00091212	Inferred_automatically	RNAi_primary
			WBRNAi00111643	Inferred_automatically	RNAi_primary
			WBRNAi00082363	Inferred_automatically	RNAi_primary
			WBRNAi00116917	Inferred_automatically	RNAi_primary
			WBRNAi00030905	Inferred_automatically	RNAi_primary
			WBRNAi00090797	Inferred_automatically	RNAi_primary
		Expr_pattern	Expr4799
			Expr9585
			Expr1021629
			Expr1033822
			Expr1148492
			Expr2011139
			Expr2029375
		Drives_construct	WBCnstr00014149
			WBCnstr00032707
		Construct_product	WBCnstr00001415
			WBCnstr00017937
			WBCnstr00032707
		Microarray_results (20)
		Expression_cluster (106)
		Interaction (63)
	Map_info	Map	I	Position	1.87613	Error	0.001737
		Positive	Positive_clone	F13G3	Inferred_automatically	From sequence, transcript, pseudogene data
		Mapping_data	Multi_point	5159
				5331
		Pseudo_map_position
	Reference	WBPaper00027822
		WBPaper00029395
		WBPaper00030897
		WBPaper00035010
		WBPaper00035192
		WBPaper00037839
		WBPaper00038491
		WBPaper00039784
		WBPaper00055090
		WBPaper00057728
	Remark	Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene