WormBase Tree Display for Gene: WBGene00008519
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| WBGene00008519 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | cyp-13B1 | |||||||
| Sequence_name | F02C12.5 | ||||||||
| Molecular_name | F02C12.5 | ||||||||
| F02C12.5.1 | |||||||||
| CE23627 | |||||||||
| Other_name | CELE_F02C12.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | cyp-13B1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-13B1 | ||||
| 3 | 27 May 2005 12:47:16 | WBPerson1983 | Event | Split_into | WBGene00044405 | ||||
| Split_into | WBGene00044405 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele | WBVar00275938 | ||||||||
| WBVar01499887 | |||||||||
| WBVar01499519 | |||||||||
| WBVar01499888 | |||||||||
| WBVar01941691 | |||||||||
| WBVar01499710 | |||||||||
| WBVar00315964 | |||||||||
| WBVar01472050 | |||||||||
| WBVar01472051 | |||||||||
| WBVar01472052 | |||||||||
| WBVar02056568 | |||||||||
| WBVar01955059 | |||||||||
| WBVar01955060 | |||||||||
| WBVar01487964 | |||||||||
| WBVar01487965 | |||||||||
| WBVar01201236 | |||||||||
| WBVar01201237 | |||||||||
| WBVar01201238 | |||||||||
| WBVar01201239 | |||||||||
| WBVar00521847 | |||||||||
| WBVar00521848 | |||||||||
| WBVar01201240 | |||||||||
| WBVar01201241 | |||||||||
| WBVar00521849 | |||||||||
| WBVar01201242 | |||||||||
| WBVar00521850 | |||||||||
| WBVar01201243 | |||||||||
| WBVar00521851 | |||||||||
| WBVar01201244 | |||||||||
| WBVar00521852 | |||||||||
| WBVar01201245 | |||||||||
| WBVar00521853 | |||||||||
| WBVar01201246 | |||||||||
| WBVar00521854 | |||||||||
| WBVar01201247 | |||||||||
| WBVar01201248 | |||||||||
| WBVar01201249 | |||||||||
| WBVar01201250 | |||||||||
| WBVar01201251 | |||||||||
| WBVar01201252 | |||||||||
| WBVar01201253 | |||||||||
| WBVar01201254 | |||||||||
| WBVar01201255 | |||||||||
| WBVar01201256 | |||||||||
| WBVar01201257 | |||||||||
| WBVar01201258 | |||||||||
| WBVar01201259 | |||||||||
| WBVar01201260 | |||||||||
| WBVar02005330 | |||||||||
| WBVar01201261 | |||||||||
| WBVar02027529 | |||||||||
| WBVar02027530 | |||||||||
| WBVar02005331 | |||||||||
| WBVar01201262 | |||||||||
| WBVar01703622 | |||||||||
| WBVar01703623 | |||||||||
| WBVar00237191 | |||||||||
| WBVar00084148 | |||||||||
| WBVar01759846 | |||||||||
| WBVar01759847 | |||||||||
| WBVar01679105 | |||||||||
| WBVar01572479 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01500067 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00030180 | ||||||||
| 00030181 | |||||||||
| 00030182 | |||||||||
| 00030183 | |||||||||
| 00116415 | |||||||||
| 00116416 | |||||||||
| 00116417 | |||||||||
| 00116418 | |||||||||
| Ortholog (58) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | cyp-13B1 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| Molecular_info | Corresponding_CDS | F02C12.5 | |||||||
| Corresponding_CDS_history | F02C12.5a:wp252 | ||||||||
| F02C12.5b:wp144 | |||||||||
| Corresponding_transcript | F02C12.5.1 | ||||||||
| Other_sequence | CBC10672_1 | ||||||||
| Associated_feature | WBsf654524 | ||||||||
| WBsf238131 | |||||||||
| WBsf238132 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00012766 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00043796 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030567 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092630 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1028044 | ||||||||
| Expr1033708 | |||||||||
| Expr1147771 | |||||||||
| Expr2010689 | |||||||||
| Expr2028928 | |||||||||
| Drives_construct | WBCnstr00032901 | ||||||||
| Construct_product | WBCnstr00032901 | ||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (276) | |||||||||
| Interaction (43) | |||||||||
| Map_info | Map | X | Position | 11.8976 | Error | 0.095803 | |||
| Positive | Positive_clone | F02C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064073 | |||||||||
| WBPaper00064934 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
