WormBase Tree Display for Gene: WBGene00008506

WBGene00008506 SMap: S_parent: Sequence: F01G10
  Identity: Version: 2
    Name: CGC_name: tkt-1 Person_evidence: WBPerson2601
      Sequence_name: F01G10.1
      Molecular_name: F01G10.1
        F01G10.1.1
        CE09163
      Other_name: CELE_F01G10.1 Accession_evidence: NDB BX284604
      Public_name: tkt-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 18 Mar 2009 15:16:46 WBPerson9133 Name_change: CGC_name: tkt-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tkt
    Allele (24)
    Strain: WBStrain00003184
      WBStrain00002783
      WBStrain00033277
    RNASeq_FPKM (74)
    GO_annotation: 00030651
      00030652
      00030653
      00030654
      00030655
      00030656
      00116408
    Ortholog: WBGene00065677 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00026255 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00074556 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00157698 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00164121 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00098434 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00135983 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00233997 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g8910 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g7481 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g7075 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g2490 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP28.g2610 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22065 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g17706 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g17204 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6818 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4125 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g13112 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_20259.g26423 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_24823.g27228 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-tkt-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold585.g4762 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00369.g10276 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04765 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014346 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g10339 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g4668 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40248000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11549 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248175 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00259406 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00289849 Trichuris muris From_analysis: WormBase-Compara
      WBGene00298154 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000000321 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            SonicParanoid
      SGD:S000006278 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            SonicParanoid
      FB:FBgn0036784 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0037607 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030909-13 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-130530-578 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11834 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11835 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:25313 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:105992 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1921669 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1933244 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
      RGD:621036 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1304767 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1593490 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00006518 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015413 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: tkt-1 encodes an ortholog of the human gene TRANSKETOLASE (TKT; OMIM:606781), which when mutated leads to Wernicke-Korsakoff syndrome (OMIM:277730). Paper_evidence: WBPaper00004637
          Curator_confirmed: WBPerson1843
            WBPerson1823
            WBPerson567
          Date_last_updated: 14 Dec 2009 00:00:00
      Automated_description: Predicted to enable thiamine pyrophosphate binding activity and transketolase activity. Predicted to be located in mitochondrion. Is an ortholog of human TKT (transketolase) and TKTL2 (transketolase like 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F01G10.1
    Corresponding_transcript: F01G10.1.1
    Other_sequence (240)
    Associated_feature: WBsf646294
      WBsf660573
      WBsf981811
      WBsf997578
      WBsf1018062
      WBsf228967
      WBsf228968
  Experimental_info: RNAi_result (43)
    Expr_pattern (12)
    Drives_construct: WBCnstr00003310
      WBCnstr00004574
      WBCnstr00012514
      WBCnstr00032914
    Construct_product: WBCnstr00032914
    Microarray_results (23)
    Expression_cluster (179)
    Interaction (166)
  Map_info: Map: IV Position: 4.56387
    Positive: Positive_clone: F01G10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene