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WormBase Tree Display for Gene: WBGene00008458

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Name Class

WBGene00008458SMapS_parentSequenceE02H1
IdentityVersion1
NameSequence_nameE02H1.6
Molecular_nameE02H1.6
E02H1.6.1
CE28286
Other_nameCELE_E02H1.6Accession_evidenceNDBBX284602
Public_nameE02H1.6
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (18)
StrainWBStrain00037116
RNASeq_FPKM (74)
GO_annotation (21)
Contained_in_operonCEOP2436
Ortholog (36)
ParalogWBGene00006391Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionE02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known asAK6, adrenal gland protein AD-004 like protein, ADLP) and of S.cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and ispredicted to likewise be a TATA box binding protein (TBP)-associatedfactor mediating activation of RNA polymerase II; E02H1.6 prefers ATPand dATP as phosphate donors; E02H1.6's biochemical activity is unusual,since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMPand shikimate acid as substrates as well; since yeast Fap7p promotespre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays,E02H1.6 is required for normally fast growth; E02H1.6 is coexpressedwith pme-2 in an operon, and thus, like PME-2, may function in DNArepair.Paper_evidenceWBPaper00005600
WBPaper00027687
WBPaper00028896
WBPaper00028897
WBPaper00028898
WBPaper00028899
Curator_confirmedWBPerson567
Date_last_updated20 Feb 2007 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and adenylate kinase activity. Predicted to be involved in nucleoside monophosphate phosphorylation and phosphorylation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human AK6 (adenylate kinase 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSE02H1.6
Corresponding_CDS_historyE02H1.6:wp54
Corresponding_transcriptE02H1.6.1
Other_sequence (35)
Associated_featureWBsf221907
Experimental_infoRNAi_resultWBRNAi00007974Inferred_automaticallyRNAi_primary
WBRNAi00012646Inferred_automaticallyRNAi_primary
WBRNAi00065873Inferred_automaticallyRNAi_primary
WBRNAi00043602Inferred_automaticallyRNAi_primary
WBRNAi00030468Inferred_automaticallyRNAi_primary
Expr_patternExpr4325
Expr1020050
Expr1033684
Expr1147592
Expr2002134
Expr2020357
Drives_constructWBCnstr00011923
WBCnstr00032949
Construct_productWBCnstr00011923
WBCnstr00032949
AntibodyWBAntibody00001104
Microarray_results (19)
Expression_cluster (99)
Interaction (101)
Map_infoPositivePositive_cloneE02H1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII1.61605
ReferenceWBPaper00027687
WBPaper00038491
WBPaper00041771
WBPaper00055090
WBPaper00065308
MethodGene