WormBase Tree Display for Gene: WBGene00008439

WBGene00008439 SMap: S_parent: Sequence: DY3
  Identity: Version: 2
    Name: CGC_name: mfb-1 Paper_evidence: WBPaper00024548
      Sequence_name: DY3.6
      Molecular_name: DY3.6
        DY3.6.1
        CE15750
      Other_name: tag-220 Curator_confirmed: WBPerson2970
        CELE_DY3.6 Accession_evidence: NDB BX284601
      Public_name: mfb-1
    DB_info: Database: AceView gene 1J356
        WormQTL gene WBGene00008439
        WormFlux gene WBGene00008439
        NDB locus_tag CELE_DY3.6
        Panther gene CAEEL|WormBase=WBGene00008439|UniProtKB=O45323
          family PTHR13123
        NCBI gene 183975
        RefSeq protein NM_059975.5
        TREEFAM TREEFAM_ID TF313070
        TrEMBL UniProtAcc O45323
        UniProt_GCRP UniProtAcc O45323
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 22 Dec 2004 08:53:54 WBPerson2970 Name_change: CGC_name: mfb-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mfb
    Allele (70)
    Strain: WBStrain00002459
      WBStrain00002900
      WBStrain00035998
    RNASeq_FPKM (74)
    GO_annotation: 00034241
      00034242
      00034243
      00034244
      00034245
      00034246
    Ortholog (40)
    Structured_description: Automated_description: Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm and nucleus. Predicted to be part of SCF ubiquitin ligase complex. Expressed in several structures, including head; hypodermal cell; tail; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human FBXO25 (F-box protein 25) and FBXO32 (F-box protein 32). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:14557 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16731)
  Molecular_info: Corresponding_CDS: DY3.6
    Corresponding_transcript: DY3.6.1
    Other_sequence (99)
    Associated_feature: WBsf649419
      WBsf984505
      WBsf984506
      WBsf1010275
      WBsf219983
  Experimental_info: RNAi_result: WBRNAi00060999 Inferred_automatically: RNAi_primary
      WBRNAi00116913 Inferred_automatically: RNAi_primary
      WBRNAi00030444 Inferred_automatically: RNAi_primary
      WBRNAi00060998 Inferred_automatically: RNAi_primary
      WBRNAi00113747 Inferred_automatically: RNAi_primary
      WBRNAi00060997 Inferred_automatically: RNAi_primary
      WBRNAi00043553 Inferred_automatically: RNAi_primary
      WBRNAi00061000 Inferred_automatically: RNAi_primary
      WBRNAi00113743 Inferred_automatically: RNAi_primary
    Expr_pattern (12)
    Drives_construct: WBCnstr00003056
      WBCnstr00004524
      WBCnstr00011153
      WBCnstr00020326
    Construct_product: WBCnstr00011153
    Microarray_results (18)
    Expression_cluster (239)
    Interaction (18)
  Map_info: Map: I Position: 3.11369 Error: 0.005753
    Positive: Positive_clone: DY3 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4889
        4741
    Pseudo_map_position
  Reference: WBPaper00012854
    WBPaper00024548
    WBPaper00038491
    WBPaper00043086
    WBPaper00046423
    WBPaper00055090
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene