WormBase Tree Display for Gene: WBGene00008133
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| WBGene00008133 | SMap | S_parent | Sequence | C47B2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | efsc-1 | Person_evidence | WBPerson5890 | |||||
| Sequence_name | C47B2.7 | ||||||||
| Molecular_name | C47B2.7a | ||||||||
| C47B2.7a.1 | |||||||||
| CE17567 | |||||||||
| C47B2.7b | |||||||||
| CE24853 | |||||||||
| C47B2.7b.1 | |||||||||
| Other_name | selb-1 | Person_evidence | WBPerson5890 | ||||||
| CELE_C47B2.7 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | efsc-1 | ||||||||
| DB_info | Database | AceView | gene | 1N573 | |||||
| WormQTL | gene | WBGene00008133 | |||||||
| WormFlux | gene | WBGene00008133 | |||||||
| NDB | locus_tag | CELE_C47B2.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00008133|UniProtKB=O62108 | |||||||
| family | PTHR43721 | ||||||||
| NCBI | gene | 173172 | |||||||
| RefSeq | protein | NM_060874.3 | |||||||
| NM_060875.6 | |||||||||
| TREEFAM | TREEFAM_ID | TF300432 | |||||||
| TrEMBL | UniProtAcc | O62108 | |||||||
| O62109 | |||||||||
| UniProt_GCRP | UniProtAcc | O62108 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 23 Feb 2007 15:37:00 | WBPerson2970 | Name_change | CGC_name | selb-1 | ||||
| 3 | 06 Dec 2013 09:35:23 | WBPerson2970 | Name_change | CGC_name | efsc-1 | ||||
| Other_name | selb-1 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | efsc | ||||||||
| Allele (135) | |||||||||
| Strain | WBStrain00032640 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00036996 | ||||||||
| 00036997 | |||||||||
| 00036998 | |||||||||
| 00116072 | |||||||||
| 00116073 | |||||||||
| Contained_in_operon | CEOP1786 | ||||||||
| Ortholog (39) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | efsc-1 encodes an ortholog of the mammalian selenocysteine-specific elongation factor SelB that binds GTP, recognizes the Sec-tRNA(Sec) in vitro and in vivo, and is required for efficient selenoprotein translation in vivo; EFSC-1 activity is required for incorporation of selenocysteine into TRXR-1, and loss of EFSC-1 activity results in molting defects similar to those seen in trxr-1 mutant animals. | Paper_evidence | WBPaper00012823 | |||||
| WBPaper00037973 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 28 May 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable translation elongation factor activity. Involved in selenocysteine incorporation. Is an ortholog of human EEFSEC (eukaryotic elongation factor, selenocysteine-tRNA specific). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C47B2.7a | |||||||
| C47B2.7b | |||||||||
| Corresponding_transcript | C47B2.7a.1 | ||||||||
| C47B2.7b.1 | |||||||||
| Other_sequence | JI168734.1 | ||||||||
| CBC05544_1 | |||||||||
| CJC05845_1 | |||||||||
| JI168862.1 | |||||||||
| Associated_feature | WBsf657003 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00003177 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00029898 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042654 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1011624 | ||||||||
| Expr1033530 | |||||||||
| Expr1146642 | |||||||||
| Expr2011194 | |||||||||
| Expr2029430 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (75) | |||||||||
| SAGE_tag | SAGE:tggaaagagtggaaaaa | Strand | Sense | ||||||
| Unambiguously_mapped | |||||||||
| SAGE:gaaacaacgtgttggcc | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:tggaaagagt | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:tccttttctg | Strand | Antisense | |||||||
| Map_info | Map | I | Position | 16.8159 | Error | 0.002029 | |||
| Positive | Positive_clone | C47B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00012823 | ||||||||
| WBPaper00019140 | |||||||||
| WBPaper00037973 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041771 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
