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WormBase Tree Display for Gene: WBGene00007646

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Name Class

WBGene00007646SMapS_parentSequenceC17E4
IdentityVersion2
NameCGC_namenkb-1Person_evidenceWBPerson919
WBPerson287
Sequence_nameC17E4.9
Molecular_nameC17E4.9a
C17E4.9a.1
CE08258
C17E4.9b
Other_nameCELE_C17E4.9Accession_evidenceNDBBX284601
Public_namenkb-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 Oct 2008 09:57:22WBPerson2970Name_changeCGC_namenkb-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnkb
Allele (34)
StrainWBStrain00031814
RNASeq_FPKM (74)
GO_annotation (17)
Contained_in_operonCEOP1544
Ortholog (59)
ParalogWBGene00010117Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00008074Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Expressed in neurons and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including atrophic gastritis; autoimmune gastritis; and essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:8929Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:820)
DOID:10825Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:804)
DOID:0040090Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:820)
DOID:10534Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:820)
Molecular_infoCorresponding_CDSC17E4.9a
Corresponding_transcriptC17E4.9b
C17E4.9a.1
Other_sequence (23)
Associated_featureWBsf643584
WBsf656741
WBsf656742
WBsf656743
WBsf1010369
WBsf218276
WBsf218277
WBsf218278
Experimental_infoRNAi_resultWBRNAi00085451Inferred_automaticallyRNAi_primary
WBRNAi00024582Inferred_automaticallyRNAi_primary
WBRNAi00029006Inferred_automaticallyRNAi_primary
WBRNAi00071041Inferred_automaticallyRNAi_primary
WBRNAi00024583Inferred_automaticallyRNAi_primary
WBRNAi00071686Inferred_automaticallyRNAi_primary
WBRNAi00106126Inferred_automaticallyRNAi_primary
WBRNAi00116734Inferred_automaticallyRNAi_primary
WBRNAi00040802Inferred_automaticallyRNAi_primary
WBRNAi00002975Inferred_automaticallyRNAi_primary
Expr_patternExpr8227
Expr8229
Expr11316
Expr1017842
Expr1033304
Expr1144844
Expr2014268
Expr2032508
Drives_constructWBCnstr00018766
Construct_productWBCnstr00013193
WBCnstr00013195
Microarray_results (25)
Expression_cluster (121)
Interaction (25)
Map_infoMapIPosition3.76304Error0.00056
PositivePositive_cloneC17E4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005423
WBPaper00010788
WBPaper00018962
WBPaper00031996
WBPaper00038491
WBPaper00043657
WBPaper00049828
WBPaper00055090
WBPaper00063976
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene