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WormBase Tree Display for Gene: WBGene00007036

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Name Class

WBGene00007036EvidenceAuthor_evidenceJensen LT
SMapS_parentSequenceZK430
IdentityVersion1
NameCGC_namesod-5
Sequence_nameZK430.3
Molecular_nameZK430.3
ZK430.3.1
CE05080
Other_nameCELE_ZK430.3Accession_evidenceNDBBX284602
Public_namesod-5
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change124 May 2004 11:37:54WBPerson1845EventCreated
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsod
Allele (18)
StrainWBStrain00026684
WBStrain00007573
WBStrain00007670
WBStrain00054749
RNASeq_FPKM (74)
GO_annotation00080055
00080056
00080057
00080058
00080059
00080060
00080061
00115244
00115245
00115246
Ortholog (26)
ParalogWBGene00004930Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00004933Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionsod-5 encodes one of five superoxide (SOD) isozymes in C. elegans; along with SOD-1, SOD-5 is predicted to be one of two cytoplasmic Cu/Zn SODs in C. elegans; sod-5 expression is increased in sod-1 mutant animals and likewise, sod-1 expression is increased in sod-5 mutants, suggesting a possible mechanism of functional compensation between these two genes; the sod-5 promoter contains one copy of a DAF-16 binding element, consistent with observations that sod-5 mRNA levels increase in insulin/IGF-1 signaling pathway mutants.Paper_evidenceWBPaper00029337
WBPaper00031533
WBPaper00032884
WBPaper00032989
Curator_confirmedWBPerson1843
Date_last_updated06 May 2009 00:00:00
Automated_descriptionPredicted to enable copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); eye disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human SOD1 (superoxide dismutase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (35)
Molecular_infoCorresponding_CDSZK430.3
Corresponding_transcriptZK430.3.1
Other_sequence (93)
Associated_featureWBsf047540
WBsf644101
WBsf987595
WBsf987596
WBsf987597
WBsf1012085
WBsf1012086
WBsf221123
Experimental_infoRNAi_resultWBRNAi00087931Inferred_automaticallyRNAi_primary
WBRNAi00076885Inferred_automaticallyRNAi_primary
WBRNAi00022012Inferred_automaticallyRNAi_primary
WBRNAi00038294Inferred_automaticallyRNAi_primary
WBRNAi00092701Inferred_automaticallyRNAi_primary
WBRNAi00087933Inferred_automaticallyRNAi_primary
WBRNAi00022014Inferred_automaticallyRNAi_primary
WBRNAi00059427Inferred_automaticallyRNAi_primary
WBRNAi00064043Inferred_automaticallyRNAi_primary
WBRNAi00087930Inferred_automaticallyRNAi_primary
Expr_patternExpr12757
Expr14239
Expr1019070
Expr1162854
Expr2015998
Expr2034233
Drives_constructWBCnstr00005465
AntibodyWBAntibody00001866
Microarray_results (18)
Expression_cluster (150)
Interaction (143)
WBProcessWBbiopr:00000096
Map_infoMapIIPosition-4.6946Error0.033727
PositivePositive_cloneZK430Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5366
5621
Pseudo_map_position
Reference (60)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene