WormBase Tree Display for Gene: WBGene00007025

WBGene00007025 Evidence: Author_evidence: Bourbon H-M
  SMap: S_parent: Sequence: K08E3
  Identity: Version: 1
    Name: CGC_name: mdt-29
      Sequence_name: K08E3.8
      Molecular_name: K08E3.8
        K08E3.8.1
        CE18874
        K08E3.8.2
      Other_name: CELE_K08E3.8 Accession_evidence: NDB BX284603
      Public_name: mdt-29
    DB_info: Database: AceView gene 3O867
        WormQTL gene WBGene00007025
        WormFlux gene WBGene00007025
        NDB locus_tag CELE_K08E3.8
        Panther gene CAEEL|WormBase=WBGene00007025|UniProtKB=Q9XUS2
          family PTHR24330
        NCBI gene 176817
        RefSeq protein NM_067446.8
        SwissProt UniProtAcc Q9XUS2
        UniProt_GCRP UniProtAcc Q9XUS2
    Species: Caenorhabditis elegans
    History: Version_change: 1 14 May 2004 11:48:16 WBPerson1845 Event: Created
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mdt
    Allele (71)
    RNASeq_FPKM (74)
    GO_annotation: 00101957
      00101958
      00101959
      00101960
      00101961
      00101962
      00101963
      00115234
    Contained_in_operon: CEOP3822
    Ortholog (23)
    Paralog: WBGene00000451 Caenorhabditis elegans From_analysis: Panther
      WBGene00000452 Caenorhabditis elegans From_analysis: Panther
      WBGene00007066 Caenorhabditis elegans From_analysis: modENCODE_Pseudogenes
    Structured_description: Concise_description: mdt-29 encodes a putative mediator subunit with a prion-like (asparagine- or glutamine-rich) domain; note that K08E3.8 is allegedly an ortholog of Drosophila INTERSEX/IX, but the actual C. elegans IX ortholog appears to be PQN-15); in yeast two-hybrid screens, MDT-29 interacts with SEL-7 and SEL-8; MDT-29 protein also self-associates; RNAi of K08E3.8 weakly enhances the two-anchor-cell phenotype of lin-12(ar170), roughly as much as sel-7 RNAi; since SEL-7 is a novel nuclear protein, MDT-29/SEL-7/SEL-8 is likely to form a nuclear complex formed in response to LIN-12 activation. Paper_evidence: WBPaper00006438
            WBPaper00006530
          Curator_confirmed: WBPerson567
          Date_last_updated: 18 Jul 2005 00:00:00
      Automated_description: Involved in lateral inhibition; positive regulation of Notch signaling pathway; and regulation of cell fate specification. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in body wall musculature. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K08E3.8
    Corresponding_transcript: K08E3.8.1
      K08E3.8.2
    Other_sequence (19)
    Associated_feature: WBsf995021
      WBsf995022
      WBsf226066
      WBsf226067
  Experimental_info: RNAi_result (19)
    Expr_pattern: Expr2134
      Expr1019714
      Expr1033014
      Expr1153990
      Expr2013481
      Expr2031715
    Microarray_results (30)
    Expression_cluster (92)
    Interaction (23)
  Map_info: Map: III Position: 21.8463 Error: 0.079098
    Positive: Positive_clone: K08E3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006438
    WBPaper00006530
    WBPaper00027707
    WBPaper00029038
    WBPaper00031331
    WBPaper00033452
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene