WormBase Tree Display for Gene: WBGene00006949

WBGene00006949 SMap: S_parent: Sequence: F38E11
  Identity: Version: 1
    Name: CGC_name: wrt-3 Person_evidence: WBPerson83
      Sequence_name: F38E11.7
      Molecular_name: F38E11.7a
        F38E11.7a.1
        CE34013
        F38E11.7b
        CE48359
        F38E11.7b.1
      Other_name: CELE_F38E11.7 Accession_evidence: NDB BX284604
      Public_name: wrt-3
    DB_info: Database: AceView gene 4K242
        WormQTL gene WBGene00006949
        WormFlux gene WBGene00006949
        NDB locus_tag CELE_F38E11.7
        Panther gene CAEEL|WormBase=WBGene00006949|UniProtKB=Q20170
          family PTHR46706
        NCBI gene 177781
        RefSeq protein NM_001307163.3
            NM_001392370.1
        SwissProt UniProtAcc Q20170
        TrEMBL UniProtAcc N1NSJ5
        UniProt_GCRP UniProtAcc Q20170
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: wrt
    Allele (50)
    Strain: WBStrain00037068
    RNASeq_FPKM (74)
    GO_annotation: 00067408
      00067409
    Ortholog (24)
    Paralog (24)
    Structured_description: Concise_description: wrt-3 encodes a hedgehog-like protein, with an N-terminal signalsequence, a Wart domain, and a region of low-complexity sequence; WRT-3is expressed in the trinucleate pharyngeal gland cell g1 beginning atthe three-fold stage of embryogenesis, in seam cells and hypodermis, andin single muscle cells and the distal tip cells of late stage larvae andadults; the Wart domain is predicted to form a cysteine-crosslinkedprotein involved in intercellular signalling, and it has subtlesimilarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 isrequired for normal growth to full size and locomotion; both of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. Paper_evidence: WBPaper00002823
            WBPaper00003717
            WBPaper00004651
            WBPaper00026841
            WBPaper00027263
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 05 Nov 2006 00:00:00
      Automated_description: Predicted to be located in extracellular region. Expressed in hermaphrodite distal tip cell; hypodermis; muscle cell; and pharyngeal gland cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F38E11.7a
      F38E11.7b
    Corresponding_CDS_history: F38E11.7:wp101
    Corresponding_transcript: F38E11.7a.1
      F38E11.7b.1
    Associated_feature: WBsf652064
  Experimental_info: RNAi_result: WBRNAi00076982 Inferred_automatically: RNAi_primary
      WBRNAi00001776 Inferred_automatically: RNAi_primary
      WBRNAi00046722 Inferred_automatically: RNAi_primary
      WBRNAi00077009 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr643
      Expr10173
      Expr1011937
      Expr1150602
      Expr2018078
      Expr2036216
    Drives_construct: WBCnstr00012468
      WBCnstr00034079
    Construct_product: WBCnstr00034079
    Microarray_results (22)
    Expression_cluster (123)
    Interaction (21)
    WBProcess: WBbiopr:00000123
  Map_info: Map: IV Position: 4.27365 Error: 0.002089
    Positive: Positive_clone: F38E11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene