WormBase Tree Display for Gene: WBGene00006946
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| WBGene00006946 | SMap | S_parent | Sequence | C34E10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | prx-10 | Paper_evidence | WBPaper00035972 | |||||
| Person_evidence | WBPerson2754 | ||||||||
| Sequence_name | C34E10.4 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | wrs-2 | ||||||||
| wars-2 | Person_evidence | WBPerson36 | |||||||
| WBPerson10953 | |||||||||
| CELE_C34E10.4 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | prx-10 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 29 Jan 2010 14:16:16 | WBPerson2970 | Name_change | CGC_name | wars-2 | ||||
| Other_name | wrs-2 | ||||||||
| 3 | 26 Jul 2010 11:40:25 | WBPerson2970 | Name_change | CGC_name | prx-10 | ||||
| Other_name | wars-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | prx | ||||||||
| Allele (47) | |||||||||
| Strain | WBStrain00034119 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (31) | |||||||||
| Contained_in_operon | CEOP3268 | ||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00006945 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | This is a complicated gene locus that produces two distinct gene products, prx-10 and wars-2/wrs-2; transcription of this locus produces a large primary transcript containing the coding potential for functionally different proteins; the transcript can be processed (by an unknown mechanism) to allow for the translation of either the 5' (PRX-10) gene product or the 3' (WARS-2) gene product; prx-10 encodes a PeRoXisome assembly factor whereas wars-2/wrs-2 encodes a tryptophanyl (W) tRNA synthetase. | Curator_confirmed | WBPerson1983 | |||||
| Date_last_updated | 16 Nov 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable tryptophan-tRNA ligase activity. Predicted to be involved in mitochondrial tryptophanyl-tRNA aminoacylation. Predicted to be located in mitochondrial matrix. Used to study obesity. Is an ortholog of human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00035972 | ||||
| Curator_confirmed | WBPerson38202 | ||||||||
| Date_last_updated | 29 Jun 2018 00:00:00 | ||||||||
| Potential_model | EFO:MONDO:0013150 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12730) | |||||
| Models_disease_asserted | WBDOannot00000573 | ||||||||
| Molecular_info | Corresponding_CDS | C34E10.4a | |||||||
| C34E10.4b | |||||||||
| Corresponding_CDS_history | C34E10.4:wp134 | ||||||||
| Corresponding_transcript | C34E10.4a.1 | ||||||||
| C34E10.4a.2 | |||||||||
| C34E10.4b.1 | |||||||||
| C34E10.4b.2 | |||||||||
| C34E10.4b.3 | |||||||||
| C34E10.4b.4 | |||||||||
| C34E10.4b.5 | |||||||||
| C34E10.4b.6 | |||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf645156 | ||||||||
| WBsf224891 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr1016304 | ||||||||
| Expr1032960 | |||||||||
| Expr1145901 | |||||||||
| Expr2015118 | |||||||||
| Expr2033356 | |||||||||
| Drives_construct | WBCnstr00037879 | ||||||||
| Construct_product | WBCnstr00037879 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (85) | |||||||||
| Interaction | WBInteraction000043588 | ||||||||
| WBInteraction000213225 | |||||||||
| WBInteraction000274248 | |||||||||
| WBInteraction000289232 | |||||||||
| WBInteraction000310475 | |||||||||
| WBInteraction000315221 | |||||||||
| WBInteraction000379995 | |||||||||
| WBInteraction000396224 | |||||||||
| WBInteraction000442642 | |||||||||
| WBInteraction000567677 | |||||||||
| Map_info | Map | III | Position | -1.86188 | Error | 0.001995 | |||
| Positive | Positive_clone | C34E10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005877 | ||||||||
| WBPaper00027315 | |||||||||
| WBPaper00035972 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049625 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059323 | |||||||||
| WBPaper00062224 | |||||||||
| Remark | dl1 : probably mitochondrial | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
