This is a complicated gene locus that produces two distinct gene products, prx-10 and wars-2/wrs-2; transcription of this locus produces a large primary transcript containing the coding potential for functionally different proteins; the transcript can be processed (by an unknown mechanism) to allow for the translation of either the 5' (PRX-10) gene product or the 3' (WARS-2) gene product; prx-10 encodes a PeRoXisome assembly factor whereas wars-2/wrs-2 encodes a tryptophanyl (W) tRNA synthetase.
Predicted to enable tryptophan-tRNA ligase activity. Predicted to be involved in mitochondrial tryptophanyl-tRNA aminoacylation. Predicted to be located in mitochondrial matrix. Used to study obesity. Is an ortholog of human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.