WormBase Tree Display for Gene: WBGene00006913
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| WBGene00006913 | SMap | S_parent | Sequence | T01H3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | vha-4 | |||||||
| Sequence_name | T01H3.1 | ||||||||
| Molecular_name | T01H3.1 | ||||||||
| T01H3.1.1 | |||||||||
| CE03595 | |||||||||
| Other_name | CELE_T01H3.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | vha-4 | ||||||||
| DB_info | Database | AceView | gene | 2I168 | |||||
| WormQTL | gene | WBGene00006913 | |||||||
| WormFlux | gene | WBGene00006913 | |||||||
| NDB | locus_tag | CELE_T01H3.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006913|UniProtKB=G5EDB8 | |||||||
| family | PTHR10263 | ||||||||
| NCBI | gene | 174272 | |||||||
| RefSeq | protein | NM_063258.9 | |||||||
| SwissProt | UniProtAcc | G5EDB8 | |||||||
| TREEFAM | TREEFAM_ID | TF314946 | |||||||
| UniProt_GCRP | UniProtAcc | G5EDB8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 15 Jun 2006 16:05:27 | WBPerson2970 | Event | Acquires_merge | WBGene00011347 | ||||
| Acquires_merge | WBGene00011347 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | vha | ||||||||
| Allele (11) | |||||||||
| Legacy_information | [Oka T, Yamamoto R, Futai M] vha for Vacuolar-type H+ ATPase. Encodes 23kD proteolipid. vha-4::GFP strongly expressed in excretory cell, rectum and two post-anal cells. Predicted gene T01H3.1. | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00013678 | ||||||||
| 00013679 | |||||||||
| 00013680 | |||||||||
| 00013681 | |||||||||
| 00013682 | |||||||||
| 00114995 | |||||||||
| 00114996 | |||||||||
| 00114997 | |||||||||
| Contained_in_operon | CEOP2316 | ||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00006910 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006911 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00006912 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | vha-4 encodes an ortholog of subunit c'' of the membrane-bound (V0)domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-4 is apredicted V-ATPase transmembrane rotor component; VHA-4 is paralogous tothe c subunits VHA-1/-2/-3, and is predicted to help carry protons fromthe cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) fortransmembrane export; VHA-4 is required for ovulation and embryogenesis,since vha-4(RNAi) animals are sterile with polyploid, unmatured oocytesand dead progeny; VHA-4 is required for alae formation, like the V0subunits VHA-1 and VHA-5, but not like the V1 subunits VHA-8 or VHA-13;vha-4 is expressed in the excretory cell, the rectum, and a pair ofcells near the anus. | Paper_evidence | WBPaper00002899 | |||||
| WBPaper00004341 | |||||||||
| WBPaper00027697 | |||||||||
| WBPaper00028773 | |||||||||
| WBPaper00028774 | |||||||||
| WBPaper00028775 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable proton transmembrane transporter activity. Involved in embryo development. Predicted to be located in membrane. Predicted to be part of proton-transporting two-sector ATPase complex, proton-transporting domain. Expressed in excretory cell and rectum. Is an ortholog of human ATP6V0B (ATPase H+ transporting V0 subunit b). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T01H3.1 | |||||||
| Corresponding_transcript | T01H3.1.1 | ||||||||
| Other_sequence (73) | |||||||||
| Associated_feature | WBsf650276 | ||||||||
| WBsf650277 | |||||||||
| WBsf665747 | |||||||||
| WBsf665748 | |||||||||
| WBsf988587 | |||||||||
| WBsf223415 | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr1400 | ||||||||
| Expr1462 | |||||||||
| Expr1016340 | |||||||||
| Expr1032930 | |||||||||
| Expr1155804 | |||||||||
| Expr2017990 | |||||||||
| Expr2036126 | |||||||||
| Drives_construct | WBCnstr00007708 | ||||||||
| WBCnstr00010291 | |||||||||
| WBCnstr00034102 | |||||||||
| Construct_product | WBCnstr00010291 | ||||||||
| WBCnstr00034102 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (109) | |||||||||
| Interaction (49) | |||||||||
| Map_info | Map | II | Position | 0.595594 | Error | 0.001171 | |||
| Positive | Positive_clone | T01H3 | Person_evidence | WBPerson5079 | |||||
| WBPerson5074 | |||||||||
| Author_evidence | Yamamoto R | ||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Data extracted from Oka et al. (1997) | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
