WormBase Tree Display for Gene: WBGene00006832
expand all nodes | collapse all nodes | view schema
| WBGene00006832 | SMap | S_parent | Sequence | C41C4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | unc-105 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C41C4.5 | ||||||||
| Molecular_name (19) | |||||||||
| Other_name | CELE_C41C4.5 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | unc-105 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00006832 | |||||
| WormFlux | gene | WBGene00006832 | |||||||
| NDB | locus_tag | CELE_C41C4.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006832|UniProtKB=Q09274 | |||||||
| family | PTHR11690 | ||||||||
| NCBI | gene | 174306 | |||||||
| RefSeq | protein | NM_001381518.2 | |||||||
| NM_001129123.3 | |||||||||
| NM_001377828.2 | |||||||||
| NM_001267210.3 | |||||||||
| NM_063301.6 | |||||||||
| NM_001381517.1 | |||||||||
| SwissProt | UniProtAcc | Q09274 | |||||||
| TrEMBL | UniProtAcc | H2FLF8 | |||||||
| H2FLF9 | |||||||||
| H2FLG0 | |||||||||
| E5QCG1 | |||||||||
| UniProt_GCRP | UniProtAcc | Q09274 | |||||||
| OMIM | gene | 600760 | |||||||
| 600761 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 09 Jan 2012 14:54:53 | WBPerson1983 | Event | Acquires_merge | WBGene00077665 | ||||
| Acquires_merge | WBGene00077665 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Allele (115) | |||||||||
| Legacy_information | Class 3 (neomorphic) alleles n490sd : small hypercontracted rigid paralytic; very poor growth; abnormal muscle structure; n490/+ similar less severe phenotype. ES3. NA (dominant) 3 (n506 (ME0) n1274). Class 1 (loss-of-function) alleles; intragenic revertants of Class 3 alleles are probably null alleles e.g. n490n804 : wildtype phenotype no behavioral or muscular abnormality. NA (Class 1) > 10. Class 3 alleles also suppressed by mutations in unc-15 unc-22 unc-45 unc- 54 etc. | ||||||||
| See also n490, n506, n785, n786, n787, n788, n795, n796, n797, n798, n799, n801, n802, n803, n804, n805, n806, n807, n808, n809, n810, n811, n812, n813, n814, n815, n816, n817, n818, n819, n820 | |||||||||
| [Reiner D]] Mac-h (Hyper-ACtivate Muscle) | |||||||||
| [C.elegansII] n490sd : small, hypercontracted, rigid paralytic; very poor growth; abnormal muscle structure. Muscle hyperactivated, sticky pumping, short.n490/+ similar but less severe phenotype. Probable neomorphic gf allele. Suppressed by mutations in unc-15, unc-22, unc-45, unc-54etc. See also sup-20.ES3. OA2 (gf): n506 (less severe; ME0), n1274. Also intragenic revertants: n490n804 (WT, no behavioral or muscular abnormality; probable null phenotype), n490n820 etc. OA>10 (ird). Cloned: encodes degenerin family member,related to amiloride-sensitive Na channels. [Park and Horvitz 1986b; MT; RW] | |||||||||
| Strain | WBStrain00026795 | ||||||||
| WBStrain00026888 | |||||||||
| WBStrain00026889 | |||||||||
| WBStrain00026890 | |||||||||
| WBStrain00026891 | |||||||||
| WBStrain00027003 | |||||||||
| WBStrain00032015 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (45) | |||||||||
| Paralog (30) | |||||||||
| Structured_description (2) | |||||||||
| Disease_info | Potential_model | DOID:0080526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10600) | ||||
| DOID:0050477 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10600,HGNC:10602) | ||||||
| DOID:4479 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10600,HGNC:10602) | ||||||
| DOID:0080528 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10602) | ||||||
| Molecular_info (5) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00029717 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00011833 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042279 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090191 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109150 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089804 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042278 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090032 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090350 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1021485 | ||||||||
| Expr1032895 | |||||||||
| Expr1146269 | |||||||||
| Expr2017835 | |||||||||
| Expr2035971 | |||||||||
| Drives_construct | WBCnstr00034129 | ||||||||
| Construct_product | WBCnstr00034129 | ||||||||
| Microarray_results (37) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction (54) | |||||||||
| WBProcess | WBbiopr:00000002 | ||||||||
| Map_info | Map | II | Position | 0.689401 | Error | 0.004244 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | C41C4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 778 | |||||||
| 779 | |||||||||
| 780 | |||||||||
| Multi_point (11) | |||||||||
| Pos_neg_data | 1362 | ||||||||
| 1430 | |||||||||
| 1435 | |||||||||
| 1440 | |||||||||
| 1445 | |||||||||
| 1449 | |||||||||
| 1453 | |||||||||
| 1486 | |||||||||
| Reference (67) | |||||||||
| Method | Gene |
