WormBase Tree Display for Gene: WBGene00006829

WBGene00006829 SMap: S_parent: Sequence: K11D2
  Identity: Version: 1
    Name: CGC_name: unc-101 Person_evidence: WBPerson261
      Sequence_name: K11D2.3
      Molecular_name: K11D2.3a
        K11D2.3a.1
        CE28050
        K11D2.3b
        CE40095
        K11D2.3c
        CE45092
        K11D2.3b.1
        K11D2.3c.1
      Other_name: CELE_K11D2.3 Accession_evidence: NDB BX284601
      Public_name: unc-101
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: unc
    Reference_allele: WBVar00088529
    Allele: WBVar00248915 Inferred_automatically: From strain object: PS529
      WBVar00248941 Inferred_automatically: From strain object: PS968
          From strain object: WM104
      WBVar00248927
      WBVar00248926
      WBVar00248922
      WBVar00248946
      WBVar00248948
      WBVar02151623
      WBVar00303979
      WBVar01433861
      WBVar01433863
      WBVar02128739
      WBVar02128740
      WBVar02150904
      WBVar01499739
      WBVar02150916
      WBVar01499204
      WBVar02150932
      WBVar00241503
      WBVar02016754
      WBVar00088529
      WBVar00267442
      WBVar00267443
      WBVar00679443
      WBVar00679444
      WBVar00679445
      WBVar00679446
      WBVar00679447
      WBVar00679448
      WBVar00679449
      WBVar00348340
      WBVar00679450
      WBVar00679451
      WBVar00348341
      WBVar00348342
      WBVar00679452
      WBVar00679453
      WBVar00348343
      WBVar00679454
      WBVar00348344
      WBVar00679455
      WBVar00348345
      WBVar00679456
      WBVar00348346
      WBVar00348347
      WBVar00679457
      WBVar00348348
      WBVar00679458
      WBVar00348349
      WBVar00679459
      WBVar00679460
      WBVar00348350
      WBVar01958245
      WBVar00679461
      WBVar00348351
      WBVar00679462
      WBVar00348352
      WBVar00348353
      WBVar00679463
      WBVar01846512
      WBVar00679464
      WBVar00679465
      WBVar00679466
      WBVar00679467
      WBVar00679468
      WBVar00679469
      WBVar01664494
      WBVar01664495
      WBVar00679470
      WBVar01664496
      WBVar01287780
      WBVar00679471
      WBVar00679472
      WBVar01287782
      WBVar01499999
      WBVar02150802
      WBVar01399227
      WBVar01714333
      WBVar01714334
      WBVar00303010
      WBVar00540911
      WBVar00540916
      WBVar00159152
      WBVar00159153
      WBVar00159154
      WBVar00159155
      WBVar00159156
      WBVar00159157
      WBVar00159158
      WBVar00159159
      WBVar00159160
      WBVar02070561
      WBVar00159161
      WBVar00159162
      WBVar01392440
      WBVar01911935
      WBVar02116725
      WBVar01498959
    Legacy_information: m1des : Coiler very sluggish moves poorly slightly Egl slightly short; resembles unc-75.
      [C.elegansII] m1des : coiler; very sluggish, moves poorly; slightly Egl; slightly short; defecation defects, abnormal FITC staining; subviable. Adult males have abnormal tails and spicules.OA>8: rh6, sy108, sy161, sy241. Mutations suppress weak Vul mutants such as let-23(sy1); Muv phenotype in combination with sli-1. Cloned: encodes clathrin adaptor protein,ortholog of mouse AP47 (>75% identity, AP47 can substitute for unc-101). [Lee et al. 1994; DR; PS]
    Strain (51)
    RNASeq_FPKM (74)
    GO_annotation (24)
    Contained_in_operon: CEOP1961
    Ortholog (42)
    Paralog: WBGene00000150 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001082 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006777 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000164 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: unc-101 encodes an adaptin orthologous to the mu1-I subunit of adaptor protein complex 1 (AP-1) that is involved in motility, egg-laying, negative regulation of LET-23 / EGF-receptor signalling, and localization of the neuronal receptors ODR-10 and GLR-1; it is broadly expressed. Paper_evidence: WBPaper00004907
          Curator_confirmed: WBPerson625
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable clathrin adaptor activity. Involved in several processes, including cilium assembly; nematode larval development; and protein localization. Predicted to be located in clathrin-coated vesicle. Predicted to be part of clathrin adaptor complex. Expressed in several structures, including germ line; head; and tail. Is an ortholog of human AP1M1 (adaptor related protein complex 1 subunit mu 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K11D2.3a
      K11D2.3b
      K11D2.3c
    Corresponding_CDS_history: K11D2.3:wp52
    Corresponding_transcript: K11D2.3a.1
      K11D2.3b.1
      K11D2.3c.1
    Other_sequence (56)
    Associated_feature: WBsf643765
      WBsf643766
      WBsf985585
      WBsf985586
      WBsf985587
      WBsf1010903
      WBsf1010904
      WBsf1010905
      WBsf1010906
      WBsf218605
  Experimental_info: RNAi_result (15)
    Expr_pattern (11)
    Drives_construct: WBCnstr00002609
      WBCnstr00010060
    Construct_product: WBCnstr00022464
      WBCnstr00022948
      WBCnstr00023052
      WBCnstr00041869
    Microarray_results (36)
    Expression_cluster (107)
    Interaction (77)
    WBProcess: WBbiopr:00000012
      WBbiopr:00000071
  Map_info: Map: I Position: 13.3125 Error: 0.03209
    Well_ordered
    Positive: Inside_rearr: dxDf2
      Positive_clone: K11D2 Inferred_automatically: From sequence, transcript, pseudogene data
        W05A3
    Mapping_data: 2_point (15)
      Multi_point (28)
      Pos_neg_data (14)
    Landmark_gene
  Reference (128)
  Method: Gene